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    Y41C4A.8 DUF3105 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176603, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Y41C4A.8
    Official Full Name
    DUF3105 domain-containing protein
    Primary source
    WormBase:WBGene00012755
    Locus tag
    CELE_Y41C4A.8
    See related
    AllianceGenome:WB:WBGene00012755
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in innate immune response. Predicted to be active in cytoplasm. Orthologous to human TP53I13 (tumor protein p53 inducible protein 13). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See Y41C4A.8 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (11706969..11708822, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene Nematode cuticle collagen N-terminal domain-containing protein Neighboring gene Digestive organ expansion factor homolog Neighboring gene Ubiquitin-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Shapira M, et al. Proc Natl Acad Sci U S A, 2006 Sep 19. PMID 16968778, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in innate immune response HEP PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    DUF3105 domain-containing protein
    NP_499515.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      11706969..11708822 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067114.4 → NP_499515.1  DUF3105 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_499515.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XWU5
      Conserved Domains (1) summary
      pfam11303
      Location:87 → 203
      DUF3105; Protein of unknown function (DUF3105)
    Nucleotide Protein
    Heading Accession and Version

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