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    amx-3 Amine oxidase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 184919, updated on 9-Dec-2024

    Summary

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    Official Symbol
    amx-3
    Official Full Name
    Amine oxidase domain-containing protein
    Primary source
    WormBase:WBGene00000139
    Locus tag
    CELE_F25C8.2
    See related
    AllianceGenome:WB:WBGene00000139
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable polyamine oxidase activity. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma. Orthologous to human PAOX (polyamine oxidase) and SMOX (spermine oxidase). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See amx-3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    6
    Sequence:
    Chromosome: V; NC_003283.11 (20898840..20903714, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Protein unc-80 Neighboring gene ncRNA Neighboring gene 4-coumarate--CoA ligase 1-like Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables polyamine oxidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Amine oxidase domain-containing protein
    NP_001256964.1
    • Confirmed by transcript evidence
    NP_001355373.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      20898840..20903714 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001368491.3 → NP_001355373.1  Amine oxidase domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0AHD3
      Conserved Domains (1) summary
      pfam01593
      Location:11 → 443
      Amino_oxidase; Flavin containing amine oxidoreductase

    2. NM_001270035.3 → NP_001256964.1  Amine oxidase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001256964.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      E0AHD4
      Conserved Domains (1) summary
      pfam01593
      Location:3 → 358
      Amino_oxidase; Flavin containing amine oxidoreductase
    Nucleotide Protein
    Heading Accession and Version

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