mig-39 HAT C-terminal dimerization domain-containing protein;Zinc finger BED domain-containing protein 39 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: mig-39
Official Full Name: HAT C-terminal dimerization domain-containing protein;Zinc finger BED domain-containing protein 39
Primary source: WormBase:WBGene00018369
Locus tag: CELE_F42H10.5
See related: AllianceGenome:WB:WBGene00018369
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable metal ion binding activity and protein dimerization activity. Acts upstream of or within with a positive effect on negative regulation of distal tip cell migration. Located in cytoplasm and nucleus. Is expressed in distal tip cell and germ line. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See mig-39 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 6

Sequence:: Chromosome: III; NC_003281.10 (8467035..8478393)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MIG-39 acts in parallel with Rac GTPases in stopping distal tip cell migration.
Title: The BED finger domain protein MIG-39 halts migration of distal tip cells in Caenorhabditis elegans.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F42H10.5 (e-PCR)
- UniSTS:310296

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables molecular_function	ND No biological Data available more info
enables protein dimerization activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within_positive_effect negative regulation of distal tip cell migration	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoplasm	IMP Inferred from Mutant Phenotype more info	PubMed
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	IMP Inferred from Mutant Phenotype more info	PubMed

General protein information

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Preferred Names: HAT C-terminal dimerization domain-containing protein;Zinc finger BED domain-containing protein 39

NP_001317876.1

Confirmed by transcript evidence

NP_498871.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

8467035..8478393

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066470.8 → NP_498871.3 Zinc finger BED domain-containing protein 39 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_498871.3

Status: REVIEWED

UniProtKB/Swiss-Prot

P34418

Conserved Domains (1) summary

pfam05699
Location:866 → 902

Dimer_Tnp_hAT; hAT family C-terminal dimerization region
NM_001330939.3 → NP_001317876.1 HAT C-terminal dimerization domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1C3NSK7

Conserved Domains (2) summary

TIGR03545
Location:388 → 499

TIGR03545; TIGR03545 family protein

pfam05699
Location:774 → 810

Dimer_Tnp_hAT; hAT family C-terminal dimerization region