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    dyf-13 Intraflagellar transport protein 56 homolog [ Caenorhabditis elegans ]

    Gene ID: 182970, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dyf-13
    Official Full Name
    Intraflagellar transport protein 56 homolog
    Primary source
    WormBase:WBGene00001129
    Locus tag
    CELE_C27H5.7
    See related
    AllianceGenome:WB:WBGene00001129
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable intraciliary transport particle B binding activity. Predicted to be involved in intraciliary anterograde transport and intraciliary transport involved in cilium assembly. Predicted to be located in cilium. Predicted to be part of intraciliary transport particle B. Predicted to be active in ciliary basal body and ciliary base. Is expressed in neurons. Orthologous to human IFT56 (intraflagellar transport 56). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dyf-13 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    12
    Sequence:
    Chromosome: II; NC_003280.10 (7168793..7171355, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Ferrochelatase Neighboring gene Transmembrane protein 180 Neighboring gene Cuticle collagen 36 Neighboring gene ncRNA Neighboring gene Glutamate-gated ChLoride channel

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional coordination of intraflagellar transport motors. Ou G, et al. Nature, 2005 Jul 28. PMID 16049494
    2. Functional genomics of intraflagellar transport-associated proteins in C. elegans. Inglis PN, et al. Methods Cell Biol, 2009. PMID 20409822
    3. The Caenorhabditis elegans nephrocystins act as global modifiers of cilium structure. Jauregui AR, et al. J Cell Biol, 2008 Mar 10. PMID 18316409, Free PMC Article
    4. Dynein-Driven Retrograde Intraflagellar Transport Is Triphasic in C. elegans Sensory Cilia. Yi P, et al. Curr Biol, 2017 May 22. PMID 28479320
    5. Mutations affecting the chemosensory neurons of Caenorhabditis elegans. Starich TA, et al. Genetics, 1995 Jan. PMID 7705621, Free PMC Article

    See all (18) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables intraciliary transport particle B binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intraciliary anterograde transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in intraciliary transport involved in cilium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ciliary basal body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in ciliary base IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cilium IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of intraciliary transport particle B IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Intraflagellar transport protein 56 homolog
    NP_741021.1
    • Confirmed by transcript evidence
    NP_741022.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      7168793..7171355 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_171019.3 → NP_741021.1  Intraflagellar transport protein 56 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741021.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8MQB6, Q95QT8
      Conserved Domains (3) summary
      sd00006
      Location:55 → 86
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:63 → 117
      TPR_11; TPR repeat
      pfam14559
      Location:385 → 452
      TPR_19; Tetratricopeptide repeat

    2. NM_171020.6 → NP_741022.1  Intraflagellar transport protein 56 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_741022.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95QT8
      Conserved Domains (3) summary
      sd00006
      Location:33 → 64
      TPR; TPR repeat [structural motif]
      pfam13414
      Location:41 → 95
      TPR_11; TPR repeat
      pfam14559
      Location:363 → 430
      TPR_19; Tetratricopeptide repeat
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95QT8.1

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