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    dhs-5 putative oxidoreductase dhs-5 [ Caenorhabditis elegans ]

    Gene ID: 173930, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dhs-5
    Official Full Name
    putative oxidoreductase dhs-5
    Primary source
    WormBase:WBGene00000969
    Locus tag
    CELE_F56D1.5
    See related
    AllianceGenome:WB:WBGene00000969
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable oxidoreductase activity. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in enteric muscle; hypodermis; and vm1. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dhs-5 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    5
    Sequence:
    Chromosome: II; NC_003280.10 (5453847..5455977)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Calexcitin-1 Neighboring gene ncRNA Neighboring gene DAZ protein 1 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of novel target genes of CeTwist and CeE/DA. Wang P, et al. Dev Biol, 2006 May 15. PMID 16480708
    2. Isolation and molecular identification of nematode surface mutants with resistance to bacterial pathogens. O'Rourke D, et al. G3 (Bethesda), 2023 May 2. PMID 36911920, Free PMC Article
    3. Distinct patterns of gene and protein expression elicited by organophosphorus pesticides in Caenorhabditis elegans. Lewis JA, et al. BMC Genomics, 2009 Apr 29. PMID 19402892, Free PMC Article
    4. Shifted Transversal Design smart-pooling for high coverage interactome mapping. Xin X, et al. Genome Res, 2009 Jul. PMID 19447967, Free PMC Article
    5. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables oxidoreductase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    putative oxidoreductase dhs-5
    NP_495035.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5453847..5455977
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062634.7 → NP_495035.1  putative oxidoreductase dhs-5 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495035.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q10130
      Conserved Domains (2) summary
      cd05356
      Location:88 → 323
      17beta-HSD1_like_SDR_c; 17-beta-hydroxysteroid dehydrogenases (17beta-HSDs) types -1, -3, and -12, -like, classical (c) SDRs
      pfam00106
      Location:89 → 274
      adh_short; short chain dehydrogenase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q10130.2

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