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    atp-5 ATP synthase subunit d, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 179541, updated on 9-Dec-2024

    Summary

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    Official Symbol
    atp-5
    Official Full Name
    ATP synthase subunit d, mitochondrial
    Primary source
    WormBase:WBGene00007385
    Locus tag
    CELE_C06H2.1
    See related
    AllianceGenome:WB:WBGene00007385
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable proton transmembrane transporter activity. Predicted to contribute to proton-transporting ATP synthase activity, rotational mechanism. Predicted to be involved in proton motive force-driven ATP synthesis. Predicted to be located in mitochondrial inner membrane. Predicted to be part of proton-transporting ATP synthase complex, coupling factor F(o). Orthologous to human ATP5PD (ATP synthase peripheral stalk subunit d). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See atp-5 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    4
    Sequence:
    Chromosome: V; NC_003283.11 (11122901..11123867, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Ubiquitin carboxyl-terminal hydrolase 7 Neighboring gene MRG domain-containing protein Neighboring gene O-acyltransferase;diacylglycerol O-acyltransferase Neighboring gene Late endosomal/lysosomal adaptor and MAPK and MTOR activator 5 Neighboring gene START domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Enhancement in the ATP level and antioxidant capacity of Caenorhabditis elegans under continuous exposure to extremely low-frequency electromagnetic field for multiple generations. Wang Y, et al. Int J Radiat Biol, 2020 Dec. PMID 32991227
    2. ASB-1, a germline-specific isoform of mitochondrial ATP synthase b subunit, is required to maintain the rate of germline development in Caenorhabditis elegans. Kawasaki I, et al. Mech Dev, 2007 Mar. PMID 17223323
    3. A proteomic view of Caenorhabditis elegans caused by short-term hypoxic stress. Li H, et al. Proteome Sci, 2010 Sep 21. PMID 20858264, Free PMC Article
    4. Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension. Zhou B, et al. Cell, 2019 Apr 4. PMID 30929899, Free PMC Article
    5. Bacterial peptidoglycan muropeptides benefit mitochondrial homeostasis and animal physiology by acting as ATP synthase agonists. Tian D, et al. Dev Cell, 2022 Feb 7. PMID 35045336, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables proton transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to proton-transporting ATP synthase activity, rotational mechanism IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proton motive force-driven ATP synthesis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in proton motive force-driven ATP synthesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in proton transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proton-transporting ATP synthase complex, coupling factor F(o) IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ATP synthase subunit d, mitochondrial
    NP_505829.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      11122901..11123867 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_073428.7 → NP_505829.1  ATP synthase subunit d, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_505829.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q17763
      Conserved Domains (1) summary
      pfam05873
      Location:13 → 155
      Mt_ATP-synt_D; ATP synthase D chain, mitochondrial (ATP5H)
    Nucleotide Protein
    Heading Accession and Version

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