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    tex-2 SMP-LTD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173997, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tex-2
    Official Full Name
    SMP-LTD domain-containing protein
    Primary source
    WormBase:WBGene00018872
    Locus tag
    CELE_F55C12.5
    See related
    AllianceGenome:WB:WBGene00018872
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lipid binding activity. Predicted to be involved in lipid transport. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Is expressed in AIYL and AIYR. Orthologous to human TEX2 (testis expressed 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See tex-2 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    10
    Sequence:
    Chromosome: II; NC_003280.10 (5867252..5873614, complement)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene UPAR/Ly6 domain-containing protein Neighboring gene Activin_recp domain-containing protein Neighboring gene DUF1248 domain-containing protein Neighboring gene Transglycosylase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. PDZD-8 and TEX-2 regulate endosomal PI(4,5)P(2) homeostasis via lipid transport to promote embryogenesis in C. elegans. Jeyasimman D, et al. Nat Commun, 2021 Oct 18. PMID 34663803, Free PMC Article
    2. A modified TurboID approach identifies tissue-specific centriolar components in C. elegans. Holzer E, et al. PLoS Genet, 2022 Apr. PMID 35442950, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    SMP-LTD domain-containing protein
    NP_495171.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5867252..5873614 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062770.6 → NP_495171.1  SMP-LTD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495171.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L079, H2L080
    Nucleotide Protein
    Heading Accession and Version

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