U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    faah-3 Amidase domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 176916, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    faah-3
    Official Full Name
    Amidase domain-containing protein
    Primary source
    WormBase:WBGene00019068
    Locus tag
    CELE_F58H7.2
    See related
    AllianceGenome:WB:WBGene00019068
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable amidase activity and fatty acid amide hydrolase activity. Predicted to be involved in fatty acid catabolic process. Human ortholog(s) of this gene implicated in obesity and substance-related disorder. Orthologous to human FAAH (fatty acid amide hydrolase). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See faah-3 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    8
    Sequence:
    Chromosome: IV; NC_003282.8 (940017..945653, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Neurotransmitter-gated ion-channel ligand-binding domain-containing protein Neighboring gene ncRNA Neighboring gene Fibronectin type-III domain-containing protein Neighboring gene Sema domain-containing protein Neighboring gene ncRNA Neighboring gene C2H2-type domain-containing protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Amino acid and protein specificity of protein fatty acylation in C. elegans. Zhang B, et al. Proc Natl Acad Sci U S A, 2024 Jan 30. PMID 38252833, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables amidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables fatty acid amide hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in fatty acid catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Amidase domain-containing protein
    NP_500017.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      940017..945653 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067616.3 → NP_500017.2  Amidase domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500017.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45089
      Conserved Domains (1) summary
      pfam01425
      Location:82 → 553
      Amidase
    Nucleotide Protein
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous