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    NagB/RpiA/CoA transferase-like superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815134, updated on 18-Sep-2024

    Summary

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    Official Full Name
    NagB/RpiA/CoA transferase-like superfamily protein
    Primary source
    TAIR:AT2G05830
    Locus tag
    AT2G05830
    See related
    Araport:AT2G05830
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    5-METHYLTHIORIBOSE KINASE 1; MTI1; T6P5.3; T6P5_3
    Summary
    Encodes a 5-methylthioribose-1-phosphate isomerase.
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    8
    Sequence:
    Chromosome: 2; NC_003071.7 (2229539..2232149)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene ARM repeat superfamily protein Neighboring gene ncRNA Neighboring gene pseudo Neighboring gene 20S proteasome subunit PAA2 Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Phloem-specific expression of Yang cycle genes and identification of novel Yang cycle enzymes in Plantago and Arabidopsis. Pommerrenig B, et al. Plant Cell, 2011 May. PMID 21540433, Free PMC Article
    2. Protein and metabolite composition of Arabidopsis stress granules. Kosmacz M, et al. New Phytol, 2019 May. PMID 30664249
    3. Targeted interactomics reveals a complex core cell cycle machinery in Arabidopsis thaliana. Van Leene J, et al. Mol Syst Biol, 2010 Aug 10. PMID 20706207, Free PMC Article
    4. Arabidopsis plasmodesmal proteome. Fernandez-Calvino L, et al. PLoS One, 2011 Apr 20. PMID 21533090, Free PMC Article
    5. Advanced proteomic analyses yield a deep catalog of ubiquitylation targets in Arabidopsis. Kim DY, et al. Plant Cell, 2013 May. PMID 23667124, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_001036262.1
    NM_001084414.1
    NM_126596.4
    NM_201699.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables S-methyl-5-thioribose-1-phosphate isomerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in L-methionine salvage from methylthioadenosine IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasmic stress granule IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in extracellular region ISM
    Inferred from Sequence Model
    more info
    		  
    located_in mitochondrion HDA PubMed 
    located_in plasmodesma HDA PubMed 

    General protein information

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    Preferred Names
    NagB/RpiA/CoA transferase-like superfamily protein
    NP_001031339.1
    • NagB/RpiA/CoA transferase-like superfamily protein; FUNCTIONS IN: GTP binding, translation initiation factor activity; INVOLVED IN: cellular biosynthetic process, translational initiation, cellular metabolic process; LOCATED IN: endomembrane system, eukaryotic translation initiation factor 2B complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase (InterPro:IPR005251), Initiation factor 2B related (InterPro:IPR000649), Initiation factor 2B alpha/beta/delta (InterPro:IPR011559); BEST Arabidopsis thaliana protein match is: NagB/RpiA/CoA transferase-like superfamily protein (TAIR:AT3G07300.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).
    NP_001077883.1
    • NagB/RpiA/CoA transferase-like superfamily protein; FUNCTIONS IN: GTP binding, translation initiation factor activity; INVOLVED IN: cellular biosynthetic process, translational initiation, cellular metabolic process; LOCATED IN: endomembrane system, eukaryotic translation initiation factor 2B complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase (InterPro:IPR005251), Initiation factor 2B related (InterPro:IPR000649), Initiation factor 2B alpha/beta/delta (InterPro:IPR011559); BEST Arabidopsis thaliana protein match is: NagB/RpiA/CoA transferase-like superfamily protein (TAIR:AT3G07300.3); Has 4761 Blast hits to 4761 proteins in 1019 species: Archae - 363; Bacteria - 1753; Metazoa - 515; Fungi - 379; Plants - 224; Viruses - 0; Other Eukaryotes - 1527 (source: NCBI BLink).
    NP_027726.1
    • NagB/RpiA/CoA transferase-like superfamily protein; FUNCTIONS IN: GTP binding, translation initiation factor activity; INVOLVED IN: cellular biosynthetic process, translational initiation, cellular metabolic process; LOCATED IN: eukaryotic translation initiation factor 2B complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase (InterPro:IPR005251), Initiation factor 2B related (InterPro:IPR000649), Initiation factor 2B alpha/beta/delta (InterPro:IPR011559); BEST Arabidopsis thaliana protein match is: NagB/RpiA/CoA transferase-like superfamily protein (TAIR:AT3G07300.2); Has 4970 Blast hits to 4968 proteins in 1028 species: Archae - 363; Bacteria - 1764; Metazoa - 514; Fungi - 399; Plants - 224; Viruses - 0; Other Eukaryotes - 1706 (source: NCBI BLink).
    NP_973428.1
    • NagB/RpiA/CoA transferase-like superfamily protein; FUNCTIONS IN: GTP binding, translation initiation factor activity; INVOLVED IN: cellular biosynthetic process, translational initiation, cellular metabolic process; LOCATED IN: endomembrane system, eukaryotic translation initiation factor 2B complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Putative translation initiation factor, aIF-2BI/5-methylthioribose-1-phosphate isomerase (InterPro:IPR005251), Initiation factor 2B related (InterPro:IPR000649), Initiation factor 2B alpha/beta/delta (InterPro:IPR011559); BEST Arabidopsis thaliana protein match is: NagB/RpiA/CoA transferase-like superfamily protein (TAIR:AT3G07300.2); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      2229539..2232149
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_201699.2 → NP_973428.1  NagB/RpiA/CoA transferase-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_973428.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ES49
      Conserved Domains (2) summary
      TIGR00512
      Location:1 → 305
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:38 → 304
      IF-2B; Initiation factor 2 subunit family

    2. NM_126596.4 → NP_027726.1  NagB/RpiA/CoA transferase-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_027726.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8L5B9, Q8LAU5, Q9ZUG4
      UniProtKB/TrEMBL
      A0A654ES49
      Conserved Domains (2) summary
      TIGR00512
      Location:10 → 353
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:86 → 352
      IF-2B; Initiation factor 2 subunit family

    3. NM_001084414.1 → NP_001077883.1  NagB/RpiA/CoA transferase-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001077883.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ES49, A8MRP9
      Conserved Domains (2) summary
      TIGR00512
      Location:3 → 307
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:40 → 306
      IF-2B; Initiation factor 2 subunit family

    4. NM_001036262.1 → NP_001031339.1  NagB/RpiA/CoA transferase-like superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001031339.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A654ES49
      Conserved Domains (2) summary
      TIGR00512
      Location:1 → 305
      salvage_mtnA; S-methyl-5-thioribose-1-phosphate isomerase
      pfam01008
      Location:38 → 304
      IF-2B; Initiation factor 2 subunit family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9ZUG4.2

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