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    CDS1 CDP-diacylglycerol synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 842541, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CDS1
    Official Full Name
    CDP-diacylglycerol synthase 1
    Primary source
    TAIR:AT1G62430
    Locus tag
    AT1G62430
    See related
    Araport:AT1G62430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ATCDS1; CDP-diacylglycerol synthase 1; F24O1.17; F24O1_17
    Summary
    Encodes a CDP-diacylglycerol synthase, involved in phospholipid biosynthesis.
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    Genomic context

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    See CDS1 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    12
    Sequence:
    Chromosome: 1; NC_003070.9 (23105905..23109534, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene DUF506 family protein (DUF506) Neighboring gene leucine-rich repeat/extensin 2 Neighboring gene Immunoglobulin E-set superfamily protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Extraplastidial cytidinediphosphate diacylglycerol synthase activity is required for vegetative development in Arabidopsis thaliana. Zhou Y, et al. Plant J, 2013 Sep. PMID 23711240
    2. Complementary DNAs encoding eukaryotic-type cytidine-5'-diphosphate-diacylglycerol synthases of two plant species. Kopka J, et al. Plant Physiol, 1997 Mar. PMID 9085581, Free PMC Article
    3. Two closely related genes of Arabidopsis encode plastidial cytidinediphosphate diacylglycerol synthases essential for photoautotrophic growth. Haselier A, et al. Plant Physiol, 2010 Jul. PMID 20442275, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    NM_104923.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphatidate cytidylyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables phosphatidate cytidylyltransferase activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables phosphatidate cytidylyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in CDP-diacylglycerol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within developmental vegetative growth IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within phospholipid biosynthetic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in mitochondrion ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    CDP-diacylglycerol synthase 1
    NP_176433.2
    • CDP-diacylglycerol synthase 1 (CDS1); CONTAINS InterPro DOMAIN/s: Phosphatidate cytidylyltransferase (InterPro:IPR000374), Phosphatidate cytidylyltransferase, eukaryota (InterPro:IPR016720); BEST Arabidopsis thaliana protein match is: cytidinediphosphate diacylglycerol synthase 2 (TAIR:AT4G22340.1); Has 7098 Blast hits to 7086 proteins in 2534 species: Archae - 0; Bacteria - 4982; Metazoa - 186; Fungi - 135; Plants - 138; Viruses - 0; Other Eukaryotes - 1657 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      23105905..23109534 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104923.4 → NP_176433.2  CDP-diacylglycerol synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_176433.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O04928, O48808
      UniProtKB/TrEMBL
      A0A178WPS5, A0A5S9WRU3
      Conserved Domains (1) summary
      PLN02594
      Location:83 → 419
      PLN02594; phosphatidate cytidylyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O04928.1

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