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    TCP3 TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841756, updated on 18-Sep-2024

    Summary

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    Official Symbol
    TCP3
    Official Full Name
    TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3
    Primary source
    TAIR:AT1G53230
    Locus tag
    AT1G53230
    See related
    Araport:AT1G53230
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    cycloidea and PCF transcription factor 3; F12M16.13; F12M16_13; TEOSINTE BRANCHED 1
    Summary
    Encodes a member of a recently identified plant transcription factor family that includes Teosinte branched 1, Cycloidea 1, and proliferating cell nuclear antigen (PCNA) factors, PCF1 and 2. Regulated by miR319. Involved in heterochronic regulation of leaf differentiation.
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    Genomic context

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    See TCP3 in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    2
    Sequence:
    Chromosome: 1; NC_003070.9 (19849788..19851725, complement)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene sodium/calcium exchanger family protein / calcium-binding EF hand family protein Neighboring gene tRNA-Ile Neighboring gene ncRNA Neighboring gene Lactate/malate dehydrogenase family protein Neighboring gene histone-lysine N-methyltransferase, H3 lysine-79 specific-like protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The TCP domain: a motif found in proteins regulating plant growth and development. Cubas P, et al. Plant J, 1999 Apr. PMID 10363373
    2. De Novo Shoot Regeneration Controlled by HEN1 and TCP3/4 in Arabidopsis. Yang W, et al. Plant Cell Physiol, 2020 Sep 1. PMID 32579181
    3. An indole-3-acetic acid carboxyl methyltransferase regulates Arabidopsis leaf development. Qin G, et al. Plant Cell, 2005 Oct. PMID 16169896, Free PMC Article
    4. TCP transcription factors interact with AS2 in the repression of class-I KNOX genes in Arabidopsis thaliana. Li Z, et al. Plant J, 2012 Jul. PMID 22380849
    5. A protracted and dynamic maturation schedule underlies Arabidopsis leaf development. Efroni I, et al. Plant Cell, 2008 Sep. PMID 18805992, Free PMC Article

    See all (22) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. De Novo Shoot Regeneration Controlled by HEN1 and TCP3/4 in Arabidopsis.
      Title: De Novo Shoot Regeneration Controlled by HEN1 and TCP3/4 in Arabidopsis.
    2. TCP3 interactions with R2R3-MYBs lead to enhanced flavonoid production, which further negatively modulates the auxin response.
      Title: TCP3 interacts with R2R3-MYB proteins, promotes flavonoid biosynthesis and negatively regulates the auxin response in Arabidopsis thaliana.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001333584.1
    NM_104201.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf development TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within leaf senescence IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of development, heterochronic IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to auxin IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3
    NP_564624.2
    • ''TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3'' (TCP3); CONTAINS InterPro DOMAIN/s: Transcription factor, TCP (InterPro:IPR005333), Transcription factor TCP subgroup (InterPro:IPR017887); BEST Arabidopsis thaliana protein match is: TCP family transcription factor 4 (TAIR:AT3G15030.3); Has 1510 Blast hits to 1508 proteins in 333 species: Archae - 0; Bacteria - 12; Metazoa - 43; Fungi - 12; Plants - 1439; Viruses - 2; Other Eukaryotes - 2 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19849788..19851725 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104201.3 → NP_564624.2  TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_564624.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81369, Q9MAH8
      UniProtKB/TrEMBL
      A0A178WDV9, A0A5S9WP86, A0A654EI17
      Conserved Domains (1) summary
      cl23822
      Location:47 → 109
      TCP; TCP family transcription factor

    2. NM_001333584.1 → NP_001322492.1  TEOSINTE BRANCHED 1, cycloidea and PCF transcription factor 3 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81369, Q9MAH8
      UniProtKB/TrEMBL
      A0A178WDV9, A0A5S9WP86, A0A654EI17
      Conserved Domains (1) summary
      cl23822
      Location:47 → 109
      TCP; TCP family transcription factor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9MAH8.1

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