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    CIPK1 CBL-interacting protein kinase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 821016, updated on 18-Sep-2024

    Summary

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    Official Symbol
    CIPK1
    Official Full Name
    CBL-interacting protein kinase 1
    Primary source
    TAIR:AT3G17510
    Locus tag
    AT3G17510
    See related
    Araport:AT3G17510
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    CBL-interacting protein kinase 1; SNF1-RELATED PROTEIN KINASE 3.16; SnRK3.16
    Summary
    Encodes a CBL-interacting protein kinase. Specifically interacts with ECT1 and ECT2.
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    Genomic context

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    See CIPK1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    12
    Sequence:
    Chromosome: 3; NC_003074.8 (5988924..5993001, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene F-box and associated interaction domains-containing protein Neighboring gene F-box family protein Neighboring gene Late embryogenesis abundant protein (LEA) family protein Neighboring gene F-box and associated interaction domains-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The Ca(2+) -regulated protein kinase CIPK1 integrates plant responses to phosphate deficiency in Arabidopsis thaliana. Lu X, et al. Plant Biol (Stuttg), 2020 Sep. PMID 32445589
    2. Arabidopsis K+ transporter HAK5-mediated high-affinity root K+ uptake is regulated by protein kinases CIPK1 and CIPK9. Lara A, et al. J Exp Bot, 2020 Aug 6. PMID 32484219, Free PMC Article
    3. Alternative complex formation of the Ca-regulated protein kinase CIPK1 controls abscisic acid-dependent and independent stress responses in Arabidopsis. D'Angelo C, et al. Plant J, 2006 Dec. PMID 17092313
    4. Multicolor bimolecular fluorescence complementation reveals simultaneous formation of alternative CBL/CIPK complexes in planta. Waadt R, et al. Plant J, 2008 Nov. PMID 18643980
    5. Novel CIPK1-associated proteins in Arabidopsis contain an evolutionarily conserved C-terminal region that mediates nuclear localization. Ok SH, et al. Plant Physiol, 2005 Sep. PMID 16113215, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Arabidopsis K+ transporter HAK5-mediated high-affinity root K+ uptake is regulated by protein kinases CIPK1 and CIPK9.
      Title: Arabidopsis K+ transporter HAK5-mediated high-affinity root K+ uptake is regulated by protein kinases CIPK1 and CIPK9.
    2. The Ca(2+) -regulated protein kinase CIPK1 integrates plant responses to phosphate deficiency in Arabidopsis thaliana.
      Title: The Ca(2+) -regulated protein kinase CIPK1 integrates plant responses to phosphate deficiency in Arabidopsis thaliana.
    3. Two proteins containing the evolutionarily conserved C-terminal region (ECT1 and ECT2) may play a critical role in relaying the cytosolic Ca(2+) signals to the nucleus, thereby regulating gene expression.
      Title: Novel CIPK1-associated proteins in Arabidopsis contain an evolutionarily conserved C-terminal region that mediates nuclear localization.
    4. by alternative complex formation with either CBL1 or CBL9, the kinase CIPK1 represents a convergence point for abscisic acid-dependent and -independent stress responses.
      Title: Alternative complex formation of the Ca-regulated protein kinase CIPK1 controls abscisic acid-dependent and independent stress responses in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_112631.3
    NM_202599.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to abscisic acid IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to osmotic stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within response to salt stress IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in plasma membrane ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    CBL-interacting protein kinase 1
    NP_566580.1
    • CBL-interacting protein kinase 1 (CIPK1); CONTAINS InterPro DOMAIN/s: Protein kinase, ATP binding site (InterPro:IPR017441), Serine/threonine-protein kinase domain (InterPro:IPR002290), NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Serine/threonine-protein kinase, active site (InterPro:IPR008271), Protein kinase-like domain (InterPro:IPR011009), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Tyrosine-protein kinase, catalytic domain (InterPro:IPR020635), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: CBL-interacting protein kinase 17 (TAIR:AT1G48260.1); Has 128786 Blast hits to 126868 proteins in 3954 species: Archae - 151; Bacteria - 15250; Metazoa - 47593; Fungi - 12814; Plants - 31341; Viruses - 523; Other Eukaryotes - 21114 (source: NCBI BLink).
    NP_974328.1
    • CBL-interacting protein kinase 1 (CIPK1); CONTAINS InterPro DOMAIN/s: NAF/FISL domain (InterPro:IPR018451), Serine/threonine-protein kinase-like domain (InterPro:IPR017442), Protein kinase-like domain (InterPro:IPR011009), Serine/threonine-protein kinase, active site (InterPro:IPR008271), NAF domain (InterPro:IPR004041), CBL-interacting protein kinase (InterPro:IPR020660), Protein kinase, catalytic domain (InterPro:IPR000719), Calcium/calmodulin-dependent protein kinase-like (InterPro:IPR020636); BEST Arabidopsis thaliana protein match is: CBL-interacting protein kinase 17 (TAIR:AT1G48260.1); Has 35333 Blast hits to 34131 proteins in 2444 species: Archae - 798; Bacteria - 22429; Metazoa - 974; Fungi - 991; Plants - 531; Viruses - 0; Other Eukaryotes - 9610 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      5988924..5993001 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_112631.3 → NP_566580.1  CBL-interacting protein kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566580.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q3EB49, Q8RWC9, Q9FUK2, Q9LUP6
      UniProtKB/TrEMBL
      A0A178VIP5, A0A5S9XDJ3, A0A7G2ENH3
      Conserved Domains (2) summary
      cd12195
      Location:319 → 432
      CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
      cd14663
      Location:19 → 274
      STKc_SnRK3; Catalytic domain of the Serine/Threonine Kinases, Sucrose nonfermenting 1-related protein kinase subfamily 3

    2. NM_202599.2 → NP_974328.1  CBL-interacting protein kinase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_974328.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A7G2ENH3
      Conserved Domains (3) summary
      cd12195
      Location:239 → 352
      CIPK_C; C-terminal regulatory domain of Calcineurin B-Like (CBL)-interacting protein kinases
      smart00220
      Location:9 → 195
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cl21453
      Location:5 → 194
      PKc_like; Protein Kinases, catalytic domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8RWC9.2

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