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    PBB1 N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 822364, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PBB1
    Official Full Name
    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
    Primary source
    TAIR:AT3G27430
    Locus tag
    AT3G27430
    See related
    Araport:AT3G27430
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    20S PROTEASOME BETA SUBUNIT PBB1
    Summary
    Encodes 20S proteasome beta subunit PBB1 (PBB1).
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    Genomic context

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    See PBB1 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    9
    Sequence:
    Chromosome: 3; NC_003074.8 (10152458..10155447)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene bromodomain testis-specific protein Neighboring gene ECA1-like gametogenesis related family protein Neighboring gene uridine kinase-like 5 Neighboring gene miscRNA Neighboring gene SGF29 tudor-like domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular organization of the 20S proteasome gene family from Arabidopsis thaliana. Fu H, et al. Genetics, 1998 Jun. PMID 9611183, Free PMC Article
    2. The 20S proteasome gene family in Arabidopsis thaliana. Parmentier Y, et al. FEBS Lett, 1997 Oct 27. PMID 9373170
    3. Structure and functional analysis of the 26S proteasome subunits from plants. Fu H, et al. Mol Biol Rep, 1999 Apr. PMID 10363660
    4. Affinity purification of the Arabidopsis 26 S proteasome reveals a diverse array of plant proteolytic complexes. Book AJ, et al. J Biol Chem, 2010 Aug 13. PMID 20516081, Free PMC Article
    5. Profiling of the Receptor for Activated C Kinase 1a (RACK1a) interaction network in Arabidopsis thaliana. Guo J, et al. Biochem Biophys Res Commun, 2019 Dec 3. PMID 31606202

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_001203060.1
    NM_180310.1

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables threonine-type endopeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis involved in protein catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within ubiquitin-dependent protein catabolic process TAS
    Traceable Author Statement
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    part_of proteasome complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of proteasome core complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of proteasome core complex TAS
    Traceable Author Statement
    more info
    		 PubMed 
    part_of proteasome core complex, beta-subunit complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein
    NP_001189989.1
    • PBB1; FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: 20S proteasome beta subunit PBB2 (TAIR:AT5G40580.3).
    NP_566818.1
    • PBB1; FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: 20S proteasome beta subunit PBB2 (TAIR:AT5G40580.2); Has 6205 Blast hits to 6204 proteins in 593 species: Archae - 869; Bacteria - 486; Metazoa - 2030; Fungi - 1274; Plants - 670; Viruses - 0; Other Eukaryotes - 876 (source: NCBI BLink).
    NP_850641.1
    • PBB1; FUNCTIONS IN: peptidase activity, endopeptidase activity, threonine-type endopeptidase activity; INVOLVED IN: ubiquitin-dependent protein catabolic process; LOCATED IN: proteasome core complex, proteasome complex; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Proteasome, beta-type subunit, conserved site (InterPro:IPR016050), Peptidase T1A, proteasome beta-subunit (InterPro:IPR000243), Proteasome, subunit alpha/beta (InterPro:IPR001353); BEST Arabidopsis thaliana protein match is: 20S proteasome beta subunit PBB2 (TAIR:AT5G40580.2); Has 6188 Blast hits to 6187 proteins in 589 species: Archae - 869; Bacteria - 478; Metazoa - 2028; Fungi - 1271; Plants - 666; Viruses - 0; Other Eukaryotes - 876 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      10152458..10155447
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_113658.3 → NP_566818.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_566818.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O23710, O81152, Q3EAZ2, Q9T0L7
      UniProtKB/TrEMBL
      A0A178VCF7, A0A5S9XHT0, C0Z2Q3
      Conserved Domains (1) summary
      cd03763
      Location:40 → 228
      proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    2. NM_001203060.1 → NP_001189989.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_001189989.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z2Q3, F4IWI5
      Conserved Domains (2) summary
      COG0638
      Location:37 → 216
      PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
      cd03763
      Location:40 → 222
      proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...

    3. NM_180310.1 → NP_850641.1  N-terminal nucleophile aminohydrolases (Ntn hydrolases) superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_850641.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      C0Z2Q3
      Conserved Domains (2) summary
      COG0638
      Location:37 → 222
      PRE1; 20S proteasome, alpha and beta subunits [Posttranslational modification, protein turnover, chaperones]
      cd03763
      Location:40 → 228
      proteasome_beta_type_7; proteasome beta type-7 subunit. The 20S proteasome, multisubunit proteolytic complex, is the central enzyme of nonlysosomal protein degradation in both the cytosol and nucleus. It is composed of 28 subunits arranged as four homoheptameric rings that ...
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O23710.2

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