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    Major facilitator superfamily protein [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 841649, updated on 18-Sep-2024

    Summary

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    Official Full Name
    Major facilitator superfamily protein
    Primary source
    TAIR:AT1G52190
    Locus tag
    AT1G52190
    See related
    Araport:AT1G52190
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtNPF1.2; F9I5.4; F9I5_4; nitrate transporter 1.11; NPF1.2; NRT1.11; NRT1/ PTR family 1.2
    Summary
    Encodes a low affinity nitrate transporter that is expressed in the plasma membrane and found in the phloem of the major veins of leaves. It is responsible for nitrate redistribution to young leaves.
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    Genomic context

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    Location:
    chromosome: 1
    Exon count:
    4
    Sequence:
    Chromosome: 1; NC_003070.9 (19434480..19439031)

    Chromosome 1 - NC_003070.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Thioesterase superfamily protein Neighboring gene PLAC8 family protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003070.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Two phloem nitrate transporters, NRT1.11 and NRT1.12, are important for redistributing xylem-borne nitrate to enhance plant growth. Hsu PK, et al. Plant Physiol, 2013 Oct. PMID 24006285, Free PMC Article
    2. Border control--a membrane-linked interactome of Arabidopsis. Jones AM, et al. Science, 2014 May 16. PMID 24833385
    3. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    4. Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana. Theologis A, et al. Nature, 2000 Dec 14. PMID 11130712

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_104099.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables low-affinity nitrate transmembrane transporter activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within nitrate transmembrane transport IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 
    located_in nucleus ISM
    Inferred from Sequence Model
    more info
    		  

    General protein information

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    Preferred Names
    Major facilitator superfamily protein
    NP_175630.1
    • Major facilitator superfamily protein; FUNCTIONS IN: transporter activity; INVOLVED IN: oligopeptide transport; LOCATED IN: membrane; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Oligopeptide transporter (InterPro:IPR000109), Major facilitator superfamily, general substrate transporter (InterPro:IPR016196); BEST Arabidopsis thaliana protein match is: Major facilitator superfamily protein (TAIR:AT3G16180.1); Has 5212 Blast hits to 5001 proteins in 870 species: Archae - 0; Bacteria - 1843; Metazoa - 575; Fungi - 389; Plants - 2143; Viruses - 0; Other Eukaryotes - 262 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003070.9 Reference assembly

      Range
      19434480..19439031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_104099.4 → NP_175630.1  Major facilitator superfamily protein [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_175630.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q8LFV0, Q93Z23, Q9M817
      UniProtKB/TrEMBL
      A0A178WAH2, A0A5S9WP68, A0A654EJF9
      Conserved Domains (1) summary
      cd17416
      Location:28 → 566
      MFS_NPF1_2; NRT1/PTR family (NPF), subfamily 1 and 2 of the Major Facilitator Superfamily of transporters
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9M817.1

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