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    PAPS3 poly(A) polymerase 3 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 819835, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PAPS3
    Official Full Name
    poly(A) polymerase 3
    Primary source
    TAIR:AT3G06560
    Locus tag
    AT3G06560
    See related
    Araport:AT3G06560
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F5E6.11; F5E6_11; poly(A) polymerase 3
    Summary
    Encodes a poly(A) polymerase. Located in the cytoplasm.
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    Genomic context

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    See PAPS3 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Sequence:
    Chromosome: 3; NC_003074.8 (2044352..2047209)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene O-acetyltransferase family protein Neighboring gene Galactose oxidase/kelch repeat superfamily protein Neighboring gene Mevalonate/galactokinase family protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of genes encoding poly(A) polymerases in plants: evidence for duplication and functional specialization. Meeks LR, et al. PLoS One, 2009 Nov 26. PMID 19956626, Free PMC Article
    2. Novel alternative splicing of mRNAs encoding poly(A) polymerases in Arabidopsis. Addepalli B, et al. Biochim Biophys Acta, 2004 Aug 12. PMID 15297145
    3. Arabidopsis mRNA polyadenylation machinery: comprehensive analysis of protein-protein interactions and gene expression profiling. Hunt AG, et al. BMC Genomics, 2008 May 14. PMID 18479511, Free PMC Article
    4. A DEK domain-containing protein modulates chromatin structure and function in Arabidopsis. Waidmann S, et al. Plant Cell, 2014 Nov. PMID 25387881, Free PMC Article
    5. Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana. Salanoubat M, et al. Nature, 2000 Dec 14. PMID 11130713

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_111532.3

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables poly(A) RNA polymerase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    poly(A) polymerase 3
    NP_187308.3
    • poly(A) polymerase 3 (PAPS3); FUNCTIONS IN: protein binding, polynucleotide adenylyltransferase activity; INVOLVED IN: RNA 3'-end processing, RNA polyadenylation, transcription; LOCATED IN: cytoplasm; EXPRESSED IN: 7 plant structures; EXPRESSED DURING: L mature pollen stage, M germinated pollen stage, 4 anthesis, petal differentiation and expansion stage; CONTAINS InterPro DOMAIN/s: Poly(A) polymerase (InterPro:IPR014492), Poly(A) polymerase, central domain (InterPro:IPR007012), Nucleotidyltransferase, class I, C-terminal-like (InterPro:IPR011068), Poly(A) polymerase, RNA-binding domain (InterPro:IPR007010); BEST Arabidopsis thaliana protein match is: nuclear poly(a) polymerase (TAIR:AT4G32850.6); Has 776 Blast hits to 768 proteins in 219 species: Archae - 0; Bacteria - 13; Metazoa - 255; Fungi - 210; Plants - 173; Viruses - 0; Other Eukaryotes - 125 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      2044352..2047209
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_111532.3 → NP_187308.3  poly(A) polymerase 3 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_187308.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q56XM9, Q7XJ92, Q9C8Z7
      UniProtKB/TrEMBL
      A0A178VCG7
      Conserved Domains (1) summary
      cl11966
      Location:12 → 332
      NT_Pol-beta-like; Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q56XM9.1

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