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    RR5 response regulator 5 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823965, updated on 18-Sep-2024

    Summary

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    Official Symbol
    RR5
    Official Full Name
    response regulator 5
    Primary source
    TAIR:AT3G48100
    Locus tag
    AT3G48100
    See related
    Araport:AT3G48100
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    ARABIDOPSIS THALIANA RESPONSE REGULATOR 2; ARR5; ATRR2; IBC6; INDUCED BY CYTOKININ 6; response regulator 5
    Summary
    Encodes a transcription repressor that mediates a negative feedback loop in cytokinin signalling. ARR5 expression is upregulated by Class I KNOX genes. Arr5 protein is stabilized by cytokinin in a two-component phosphorelay.
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    Genomic context

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    See RR5 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    5
    Sequence:
    Chromosome: 3; NC_003074.8 (17758427..17760950, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene RING/U-box superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene alpha/beta-Hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene glycine-tRNA ligase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. AXR1 promotes the Arabidopsis cytokinin response by facilitating ARR5 proteolysis. Li Y, et al. Plant J, 2013 Apr. PMID 23279608
    2. Two genes with similarity to bacterial response regulators are rapidly and specifically induced by cytokinin in Arabidopsis. Brandstatter I, et al. Plant Cell, 1998 Jun. PMID 9634588, Free PMC Article
    3. Type-A Arabidopsis response regulators are partially redundant negative regulators of cytokinin signaling. To JP, et al. Plant Cell, 2004 Mar. PMID 14973166, Free PMC Article
    4. Characterization of the response of the Arabidopsis response regulator gene family to cytokinin. D'Agostino IB, et al. Plant Physiol, 2000 Dec. PMID 11115887, Free PMC Article
    5. Destabilization of interaction between cytokinin signaling intermediates AHP1 and ARR4 modulates Arabidopsis development. Verma V, et al. New Phytol, 2015 Apr. PMID 25643735

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_114679.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables phosphorelay response regulator activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables phosphorelay response regulator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within circadian rhythm IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin-activated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within cytokinin-activated signaling pathway TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of DNA-templated transcription TAS
    Traceable Author Statement
    more info
    		 PubMed 
    acts_upstream_of_or_within response to cytokinin IEP
    Inferred from Expression Pattern
    more info
    		 PubMed 
    acts_upstream_of_or_within response to red light IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in cytoplasm ISM
    Inferred from Sequence Model
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    response regulator 5
    NP_190393.1
    • response regulator 5 (RR5); CONTAINS InterPro DOMAIN/s: CheY-like (InterPro:IPR011006), Signal transduction response regulator, receiver domain (InterPro:IPR001789); BEST Arabidopsis thaliana protein match is: response regulator 6 (TAIR:AT5G62920.1); Has 45766 Blast hits to 45301 proteins in 2636 species: Archae - 240; Bacteria - 40380; Metazoa - 18; Fungi - 471; Plants - 1420; Viruses - 2; Other Eukaryotes - 3235 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17758427..17760950 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114679.4 → NP_190393.1  response regulator 5 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190393.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80364, Q9SB04, Q9SBH9
      UniProtKB/TrEMBL
      A0A178V7A6, A0A384KWJ6, A0A654FDU9, Q0WW39
      Conserved Domains (1) summary
      cd17581
      Location:27 → 149
      REC_typeA_ARR; phosphoacceptor receiver (REC) domain of type A Arabidopsis response regulators (ARRs) and similar proteins
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SB04.2

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