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    ALDH2B4 aldehyde dehydrogenase 2B4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 823955, updated on 18-Sep-2024

    Summary

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    Official Symbol
    ALDH2B4
    Official Full Name
    aldehyde dehydrogenase 2B4
    Primary source
    TAIR:AT3G48000
    Locus tag
    AT3G48000
    See related
    Araport:AT3G48000
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    aldehyde dehydrogenase 2; ALDEHYDE DEHYDROGENASE 2; aldehyde dehydrogenase 2A; aldehyde dehydrogenase 2B4; ALDH2; ALDH2A
    Summary
    Encodes a putative (NAD+) aldehyde dehydrogenase.
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    Genomic context

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    See ALDH2B4 in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    11
    Sequence:
    Chromosome: 3; NC_003074.8 (17716864..17720169, complement)

    Chromosome 3 - NC_003074.8Genomic Context describing neighboring genes Neighboring gene Integral membrane HPP family protein Neighboring gene SUGAR-INSENSITIVE 3 Neighboring gene cyclic nucleotide-gated channel 16 Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003074.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The roles of aldehyde dehydrogenases (ALDHs) in the PDH bypass of Arabidopsis. Wei Y, et al. BMC Biochem, 2009 Mar 25. PMID 19320993, Free PMC Article
    2. Characterization of the aldehyde dehydrogenase gene families of Zea mays and Arabidopsis. Skibbe DS, et al. Plant Mol Biol, 2002 Mar-Apr. PMID 11999848
    3. Analysis of the soluble ATP-binding proteome of plant mitochondria identifies new proteins and nucleotide triphosphate interactions within the matrix. Ito J, et al. J Proteome Res, 2006 Dec. PMID 17137349
    4. Heterogeneity of the mitochondrial proteome for photosynthetic and non-photosynthetic Arabidopsis metabolism. Lee CP, et al. Mol Cell Proteomics, 2008 Jul. PMID 18385124
    5. Analysis of the Arabidopsis mitochondrial proteome. Millar AH, et al. Plant Physiol, 2001 Dec. PMID 11743115, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    NM_114669.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ATP binding HDA PubMed 
    enables aldehyde dehydrogenase (NAD+) activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    enables glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chloroplast ISM
    Inferred from Sequence Model
    more info
    		  
    located_in cytosol HDA PubMed 
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    aldehyde dehydrogenase 2B4
    NP_190383.1
    • aldehyde dehydrogenase 2B4 (ALDH2B4); FUNCTIONS IN: 3-chloroallyl aldehyde dehydrogenase activity, aldehyde dehydrogenase (NAD) activity, ATP binding; INVOLVED IN: response to cadmium ion; LOCATED IN: mitochondrion, chloroplast; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 14 growth stages; CONTAINS InterPro DOMAIN/s: Aldehyde/histidinol dehydrogenase (InterPro:IPR016161), Aldehyde dehydrogenase (InterPro:IPR015590), Aldehyde dehydrogenase, N-terminal (InterPro:IPR016162), Aldehyde dehydrogenase, conserved site (InterPro:IPR016160); BEST Arabidopsis thaliana protein match is: aldehyde dehydrogenase 2B7 (TAIR:AT1G23800.1); Has 61695 Blast hits to 61296 proteins in 3003 species: Archae - 476; Bacteria - 35240; Metazoa - 2662; Fungi - 2127; Plants - 1668; Viruses - 0; Other Eukaryotes - 19522 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003074.8 Reference assembly

      Range
      17716864..17720169 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_114669.4 → NP_190383.1  aldehyde dehydrogenase 2B4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_190383.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q42090, Q9SU63
      UniProtKB/TrEMBL
      A0A178VKH7
      Conserved Domains (2) summary
      cd07142
      Location:55 → 530
      ALDH_F2BC; Arabidosis aldehyde dehydrogenase family 2 B4, B7, C4-like
      PLN02466
      Location:1 → 538
      PLN02466; aldehyde dehydrogenase family 2 member
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SU63.1

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