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    arpp21 cAMP-regulated phosphoprotein, 21 [ Danio rerio (zebrafish) ]

    Gene ID: 564134, updated on 9-Dec-2024

    Summary

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    Official Symbol
    arpp21provided by ZNC
    Official Full Name
    cAMP-regulated phosphoprotein, 21provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-081104-296
    See related
    Ensembl:ENSDARG00000061081 AllianceGenome:ZFIN:ZDB-GENE-081104-296
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb474; sb:cb474; wu:fb72d03; si:ch73-92o9.2
    Summary
    Predicted to enable nucleic acid binding activity. Predicted to be active in cytoplasm. Is expressed in adaxial cell; myotome; and somite. Orthologous to human ARPP21 (cAMP regulated phosphoprotein 21). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See arpp21 in Genome Data Viewer
    Location:
    chromosome: 19
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 19 NC_007130.7 (42886415..42917231)
    105 previous assembly GRCz10 (GCF_000002035.5) 19 NC_007130.6 (43316914..43347794)

    Chromosome 19 - NC_007130.7Genomic Context describing neighboring genes Neighboring gene upstream binding protein 1 Neighboring gene programmed cell death 6 interacting protein Neighboring gene microRNA 128-2 Neighboring gene zinc finger TRAF-type containing 1 Neighboring gene doublecortin-like kinase 3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Crtap and p3h1 knock out zebrafish support defective collagen chaperoning as the cause of their osteogenesis imperfecta phenotype. Tonelli F, et al. Matrix Biol, 2020 Aug. PMID 32173581
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    cAMP-regulated phosphoprotein 21
    Names
    cAMP-regulated phosphoprotein, 21kDa
    cyclic AMP-regulated phosphoprotein, 21

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007130.7 Reference GRCz11 Primary Assembly

      Range
      42886415..42917231
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_687493.9 → XP_692585.5  cAMP-regulated phosphoprotein 21 isoform X1

      UniProtKB/TrEMBL
      A0A2R9YJI6, A0A8N7UR40
      Related
      ENSDARP00000126062.1, ENSDART00000151298.3
      Conserved Domains (1) summary
      cd02642
      Location:137 → 197
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

    2. XM_005159755.5 → XP_005159812.1  cAMP-regulated phosphoprotein 21 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B6J9
      Conserved Domains (1) summary
      cd02642
      Location:137 → 197
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

    3. XM_005159754.5 → XP_005159811.1  cAMP-regulated phosphoprotein 21 isoform X2

      UniProtKB/TrEMBL
      A0A8M2B6M6
      Related
      ENSDARP00000126087.3, ENSDART00000051724.7
      Conserved Domains (1) summary
      cd02642
      Location:137 → 197
      R3H_encore_like; R3H domain of encore-like and DIP1-like proteins. Drosophila encore is involved in the germline exit after four mitotic divisions, by facilitating SCF-ubiquitin-proteasome-dependent proteolysis. Maize DBF1-interactor protein 1 (DIP1) containing an R3H ...

    4. XM_068215328.1 → XP_068071429.1  cAMP-regulated phosphoprotein 21 isoform X4

    Nucleotide Protein Strain
    Heading Accession and Version

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