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    kifc3 kinesin family member C3 [ Danio rerio (zebrafish) ]

    Gene ID: 568367, updated on 9-Dec-2024

    Summary

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    Official Symbol
    kifc3provided by ZNC
    Official Full Name
    kinesin family member C3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-3724
    See related
    AllianceGenome:ZFIN:ZDB-GENE-030131-3724
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fc51b05; wu:fc51b05; si:ch211-160j6.2
    Summary
    Predicted to enable microtubule binding activity. Predicted to be involved in microtubule-based process. Predicted to act upstream of or within microtubule-based movement. Predicted to be located in cytoplasm and microtubule. Predicted to be active in microtubule cytoskeleton. Orthologous to human KIFC3 (kinesin family member C3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See kifc3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (45526550..45592410)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (45529560..45595456)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene LARGE xylosyl- and glucuronyltransferase 2 Neighboring gene uncharacterized LOC110438109 Neighboring gene cyclic nucleotide gated channel subunit beta 1a Neighboring gene uncharacterized LOC108180032 Neighboring gene WT1 transcription factor b Neighboring gene eukaryotic translation initiation factor 3, subunit M

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary. Zeng S, et al. Gene, 2002 Jul 10. PMID 12234666
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables microtubule motor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within microtubule-based movement IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in system development IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    kinesin-like protein KIFC3
    Names
    novel kinesin motor domain containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      45526550..45592410
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068214958.1 → XP_068071059.1  kinesin-like protein KIFC3 isoform X13

      UniProtKB/TrEMBL
      A0A8M9PFZ6

    2. XM_009293855.3 → XP_009292130.1  kinesin-like protein KIFC3 isoform X14

      See identical proteins and their annotated locations for XP_009292130.1

      UniProtKB/TrEMBL
      A0A8M3B361, A0A8M9PFZ6
      Conserved Domains (4) summary
      smart00129
      Location:566 → 895
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01366
      Location:564 → 891
      KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
      pfam15619
      Location:208 → 386
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
      cl01090
      Location:362 → 407
      SlyX; SlyX

    3. XM_068214961.1 → XP_068071062.1  kinesin-like protein KIFC3 isoform X16

      UniProtKB/TrEMBL
      A0A8M9PFZ6

    4. XM_068214962.1 → XP_068071063.1  kinesin-like protein KIFC3 isoform X17

      UniProtKB/TrEMBL
      A0A8M9PFZ6

    5. XM_068214947.1 → XP_068071048.1  kinesin-like protein KIFC3 isoform X1

      UniProtKB/TrEMBL
      A0A8M3AV59

    6. XM_068214950.1 → XP_068071051.1  kinesin-like protein KIFC3 isoform X5

      UniProtKB/TrEMBL
      A0A8M3AS77

    7. XM_068214948.1 → XP_068071049.1  kinesin-like protein KIFC3 isoform X2

      UniProtKB/TrEMBL
      A0A8M3AV59

    8. XM_068214949.1 → XP_068071050.1  kinesin-like protein KIFC3 isoform X3

      UniProtKB/TrEMBL
      A0A8M2B5V3

    9. XM_068214951.1 → XP_068071052.1  kinesin-like protein KIFC3 isoform X6

      UniProtKB/TrEMBL
      A0A8M3AS77

    10. XM_068214952.1 → XP_068071053.1  kinesin-like protein KIFC3 isoform X7

      UniProtKB/TrEMBL
      A0A8M3AS77

    11. XM_009293849.4 → XP_009292124.1  kinesin-like protein KIFC3 isoform X4

      UniProtKB/TrEMBL
      A0A8M3AKN3, A0A8M3AV59
      Conserved Domains (5) summary
      smart00129
      Location:679 → 1008
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01366
      Location:677 → 1004
      KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
      pfam05667
      Location:93 → 438
      DUF812; Protein of unknown function (DUF812)
      pfam15619
      Location:321 → 499
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
      cl01090
      Location:475 → 520
      SlyX; SlyX

    12. XM_068214953.1 → XP_068071054.1  kinesin-like protein KIFC3 isoform X8

      UniProtKB/TrEMBL
      A0A8M3AS77

    13. XM_068214954.1 → XP_068071055.1  kinesin-like protein KIFC3 isoform X9

      UniProtKB/TrEMBL
      A0A8M3AS77

    14. XM_009293853.4 → XP_009292128.1  kinesin-like protein KIFC3 isoform X10

      UniProtKB/TrEMBL
      A0A8M3AJU8, A0A8M3AS77
      Conserved Domains (5) summary
      TIGR02559
      Location:388 → 551
      HrpB7; type III secretion protein HrpB7
      smart00129
      Location:648 → 977
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01366
      Location:646 → 973
      KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
      pfam01442
      Location:301 → 443
      Apolipoprotein; Apolipoprotein A1/A4/E domain
      pfam15035
      Location:388 → 543
      Rootletin; Ciliary rootlet component, centrosome cohesion

    15. XM_068214955.1 → XP_068071056.1  kinesin-like protein KIFC3 isoform X11

      UniProtKB/TrEMBL
      A0A8M3AS77

    16. XM_068214957.1 → XP_068071058.1  kinesin-like protein KIFC3 isoform X13

      UniProtKB/TrEMBL
      A0A8M9PFZ6

    17. XM_009293854.4 → XP_009292129.1  kinesin-like protein KIFC3 isoform X14

      See identical proteins and their annotated locations for XP_009292129.1

      UniProtKB/TrEMBL
      A0A8M3B361, A0A8M9PFZ6
      Conserved Domains (4) summary
      smart00129
      Location:566 → 895
      KISc; Kinesin motor, catalytic domain. ATPase
      cd01366
      Location:564 → 891
      KISc_C_terminal; Kinesin motor domain, KIFC2/KIFC3/ncd-like carboxy-terminal kinesins
      pfam15619
      Location:208 → 386
      Lebercilin; Ciliary protein causing Leber congenital amaurosis disease
      cl01090
      Location:362 → 407
      SlyX; SlyX

    18. XM_068214956.1 → XP_068071057.1  kinesin-like protein KIFC3 isoform X12

      UniProtKB/TrEMBL
      A0A8M9PAK5

    19. XM_068214960.1 → XP_068071061.1  kinesin-like protein KIFC3 isoform X15

      UniProtKB/TrEMBL
      A0A8M9PFZ6

    20. XM_068214959.1 → XP_068071060.1  kinesin-like protein KIFC3 isoform X15

      UniProtKB/TrEMBL
      A0A8M9PFZ6
    Nucleotide Protein Strain
    Heading Accession and Version

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