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    ivns1abpb influenza virus NS1A binding protein b [ Danio rerio (zebrafish) ]

    Gene ID: 334334, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ivns1abpbprovided by ZNC
    Official Full Name
    influenza virus NS1A binding protein bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6266
    See related
    Ensembl:ENSDARG00000013946 AllianceGenome:ZFIN:ZDB-GENE-030131-6266
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fi13f08; fi41c09; wu:fi13f08; wu:fi41c09
    Summary
    Predicted to enable ubiquitin-like ligase-substrate adaptor activity. Predicted to be involved in proteasome-mediated ubiquitin-dependent protein catabolic process. Predicted to be located in cytoskeleton and nucleus. Predicted to be part of Cul3-RING ubiquitin ligase complex. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 70. Orthologous to human IVNS1ABP (influenza virus NS1A binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See ivns1abpb in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (23379401..23390742, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (23723750..23735091, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene niban apoptosis regulator 1b Neighboring gene ring finger protein 2 Neighboring gene serine/threonine-protein kinase pim-1-like Neighboring gene uncharacterized LOC137487495

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Characterization of retinoid-X receptor genes rxra, rxrba, rxrbb and rxrg during zebrafish development. Tallafuss A, et al. Gene Expr Patterns, 2006 Jun. PMID 16448862
    2. Analyses of mRNA structure dynamics identify embryonic gene regulatory programs. Beaudoin JD, et al. Nat Struct Mol Biol, 2018 Aug. PMID 30061596, Free PMC Article
    3. Expressed sequence tag analysis of expression profiles of zebrafish testis and ovary. Zeng S, et al. Gene, 2002 Jul 10. PMID 12234666
    4. Temporal pattern of loss/persistence of duplicate genes involved in signal transduction and metabolic pathways after teleost-specific genome duplication. Sato Y, et al. BMC Evol Biol, 2009 Jun 5. PMID 19500364, Free PMC Article
    5. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ubiquitin-like ligase-substrate adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of Cul3-RING ubiquitin ligase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    influenza virus NS1A-binding protein homolog B
    Names
    NS1-BP homolog B
    NS1-binding protein homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201483.1 → NP_958891.1  influenza virus NS1A-binding protein homolog B

      See identical proteins and their annotated locations for NP_958891.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045449
      UniProtKB/Swiss-Prot
      Q7ZVQ8
      Related
      ENSDARP00000002476.6, ENSDART00000020136.8
      Conserved Domains (6) summary
      smart00612
      Location:557 → 603
      Kelch; Kelch domain
      smart00875
      Location:135 → 233
      BACK; BTB And C-terminal Kelch
      PHA03098
      Location:23 → 633
      PHA03098; kelch-like protein; Provisional
      sd00038
      Location:499 → 542
      Kelch; KELCH repeat [structural motif]
      pfam00651
      Location:22 → 127
      BTB; BTB/POZ domain
      pfam01344
      Location:592 → 632
      Kelch_1; Kelch motif

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      23379401..23390742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q7ZVQ8.1 GenPept UniProtKB/Swiss-Prot:Q7ZVQ8

    Gene LinkOut

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