nat10 N-acetyltransferase 10 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: nat10provided by ZNC
Official Full Name: N-acetyltransferase 10provided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1543
See related: Ensembl:ENSDARG00000054259 AllianceGenome:ZFIN:ZDB-GENE-040426-1543
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:66119
Summary: Predicted to enable rRNA cytidine N-acetyltransferase activity and tRNA binding activity. Predicted to be involved in rRNA acetylation involved in maturation of SSU-rRNA. Predicted to act upstream of or within rRNA processing and tRNA processing. Predicted to be located in nucleus. Predicted to be active in nucleolus. Is expressed in several structures, including alar plate midbrain region; immature eye; nervous system; neural plate; and segmental plate. Orthologous to human NAT10 (N-acetyltransferase 10). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 18

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	18	NC_007129.7 (38216816..38244869, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	18	NC_007129.6 (38235808..38263861, complement)

Chromosome 18 - NC_007129.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function.
Title: Deficiency of Acetyltransferase nat10 in Zebrafish Causes Developmental Defects in the Visual Function.

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables N-acetyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity	IEA Inferred from Electronic Annotation more info
enables acyltransferase activity, transferring groups other than amino-acyl groups	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info
enables rRNA cytidine N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables tRNA N-acetyltransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables tRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in rRNA acetylation involved in maturation of SSU-rRNA	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within rRNA metabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within rRNA processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA acetylation	IBA Inferred from Biological aspect of Ancestor more info
involved_in tRNA acetylation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA wobble cytosine modification	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in nucleolus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: RNA cytidine acetyltransferase

NP_956938.1

EC 2.3.1.-

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_200644.1 → NP_956938.1 RNA cytidine acetyltransferase

See identical proteins and their annotated locations for NP_956938.1

Status: PROVISIONAL

Source sequence(s)

BC057462

UniProtKB/TrEMBL

Q6PFQ5

Related

ENSDARP00000070873.4, ENSDART00000076399.5

Conserved Domains (5) summary

COG1444
Location:24 → 908

TmcA; tRNA(Met) C34 N-acetyltransferase TmcA [Translation, ribosomal structure and biogenesis]

pfam05127
Location:283 → 482

Helicase_RecD; Helicase

pfam08351
Location:109 → 203

DUF1726; Domain of unknown function (DUF1726)

pfam13718
Location:530 → 754

GNAT_acetyltr_2; GNAT acetyltransferase 2

pfam13725
Location:777 → 894

tRNA_bind_2; Possible tRNA binding domain