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    rps3 ribosomal protein S3 [ Danio rerio (zebrafish) ]

    Gene ID: 336550, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rps3provided by ZNC
    Official Full Name
    ribosomal protein S3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-8494
    See related
    Ensembl:ENSDARG00000103007 AllianceGenome:ZFIN:ZDB-GENE-030131-8494
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    fb13d09; zgc:56088; wu:fb13d09
    Summary
    Predicted to be a structural constituent of ribosome. Acts upstream of or within chordate embryonic development and erythrocyte differentiation. Predicted to be located in mitochondrial inner membrane; ribosome; and spindle. Predicted to be part of cytosolic small ribosomal subunit. Predicted to be active in nucleus. Orthologous to human RPS3 (ribosomal protein S3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See rps3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (3038173..3049799)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (3045142..3056768, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene NACHT and WD repeat domain-containing protein 2-like Neighboring gene NACHT and WD repeat domain-containing protein 2 Neighboring gene small nucleolar RNA SNORD15 Neighboring gene small nucleolar RNA SNORD15 Neighboring gene small nucleolar RNA SNORD15 Neighboring gene small nucleolar RNA SNORD15 Neighboring gene potassium channel tetramerization domain containing 14 Neighboring gene integrator complex subunit 4 Neighboring gene adipogenesis associated, Mth938 domain containing

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Ribosomal protein deficiency causes Tp53-independent erythropoiesis failure in zebrafish. Yadav GV, et al. Int J Biochem Cell Biol, 2014 Apr. PMID 24417973
    2. Znf598-mediated Rps10/eS10 ubiquitination contributes to the ribosome ubiquitination dynamics during zebrafish development. Ugajin N, et al. RNA, 2023 Dec. PMID 37751929, Free PMC Article
    3. Ribosomal protein gene knockdown causes developmental defects in zebrafish. Uechi T, et al. PLoS One, 2006 Dec 20. PMID 17183665, Free PMC Article
    4. An in silico mining for simple sequence repeats from expressed sequence tags of zebrafish, medaka, Fundulus, and Xiphophorus. Ju Z, et al. In Silico Biol, 2005. PMID 16268789
    5. Anti-apoptotic effects of IGF-I on mortality and dysmorphogenesis in tbx5-deficient zebrafish embryos. Tsai TC, et al. BMC Dev Biol, 2018 Mar 5. PMID 29506474, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Clone Names

    • MGC56088

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables class I DNA-(apurinic or apyrimidinic site) endonuclease activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within apoptotic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within chordate embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within erythrocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of apoptotic signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of cytosolic small ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial inner membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small ribosomal subunit IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    small ribosomal subunit protein uS3
    Names
    40S ribosomal protein S3
    NP_957447.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201153.1 → NP_957447.1  small ribosomal subunit protein uS3

      See identical proteins and their annotated locations for NP_957447.1

      Status: PROVISIONAL

      Source sequence(s)
      BC045902
      UniProtKB/TrEMBL
      Q7ZVD9
      Related
      ENSDARP00000132180.1, ENSDART00000162657.2
      Conserved Domains (3) summary
      cd02413
      Location:15 → 95
      40S_S3_KH; K homology RNA-binding (KH) domain of the eukaryotic 40S small ribosomal subunit protein S3. S3 is part of the head region of the 40S ribosomal subunit and is believed to interact with mRNA as it threads its way from the latch into the channel. The KH ...
      PTZ00084
      Location:4 → 216
      PTZ00084; 40S ribosomal protein S3; Provisional
      pfam00189
      Location:105 → 186
      Ribosomal_S3_C; Ribosomal protein S3, C-terminal domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      3038173..3049799
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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