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    phf23a PHD finger protein 23a [ Danio rerio (zebrafish) ]

    Gene ID: 541372, updated on 9-Dec-2024

    Summary

    Official Symbol
    phf23aprovided by ZNC
    Official Full Name
    PHD finger protein 23aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050320-67
    See related
    Ensembl:ENSDARG00000030887 AllianceGenome:ZFIN:ZDB-GENE-050320-67
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    phf23; fb36g07; wu:fa04c06; wu:fb36g07; wu:fb71c05; zgc:112942
    Summary
    Predicted to enable metal ion binding activity. Predicted to be involved in negative regulation of autophagosome assembly; negative regulation of autophagosome maturation; and positive regulation of protein ubiquitination. Predicted to act upstream of or within autophagy. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Orthologous to human PHF23 (PHD finger protein 23). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See phf23a in Genome Data Viewer
    Location:
    chromosome: 5
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 5 NC_007116.7 (24240321..24245201, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 5 NC_007116.6 (23736521..23741401, complement)

    Chromosome 5 - NC_007116.7Genomic Context describing neighboring genes Neighboring gene SUMO specific peptidase 3a Neighboring gene phospholipid scramblase 3a Neighboring gene ATPase H+ transporting V1 subunit Aa Neighboring gene si:ch211-137i24.12

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within autophagy IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of autophagosome assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of autophagosome assembly ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of autophagosome maturation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of autophagosome maturation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013499.1NP_001013517.1  PHD finger protein 23A

      See identical proteins and their annotated locations for NP_001013517.1

      Status: PROVISIONAL

      Source sequence(s)
      BC091667
      UniProtKB/Swiss-Prot
      Q5BJ10
      UniProtKB/TrEMBL
      A8E514
      Related
      ENSDARP00000042480.5, ENSDART00000042481.6
      Conserved Domains (1) summary
      cl22851
      Location:241284
      PHD_SF; PHD finger superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007116.7 Reference GRCz11 Primary Assembly

      Range
      24240321..24245201 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394575.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      256850..261730 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)