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    mcmbp minichromosome maintenance complex binding protein [ Danio rerio (zebrafish) ]

    Gene ID: 321119, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mcmbpprovided by ZNC
    Official Full Name
    minichromosome maintenance complex binding proteinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-9676
    See related
    Ensembl:ENSDARG00000055314 AllianceGenome:ZFIN:ZDB-GENE-030131-9676
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb136; MCM-BP; sb:cb136; c10orf119; zgc:55981; wu:fi19h07
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in DNA-templated DNA replication and sister chromatid cohesion. Predicted to act upstream of or within DNA replication and cell division. Predicted to be located in nucleus. Predicted to be part of MCM complex. Is expressed in several structures, including alar plate midbrain region; blood; immature eye; nervous system; and ventral mesoderm. Orthologous to human MCMBP (minichromosome maintenance complex binding protein). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See mcmbp in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (25535043..25548882, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (25404593..25418432, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene TIA1 cytotoxic granule-associated RNA binding protein-like 1 Neighboring gene BCL2 associated athanogene 3 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene SEC23 interacting protein Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Characterization of a BAC library from channel catfish Ictalurus punctatus: indications of high levels of chromosomal reshuffling among teleost genomes. Wang S, et al. Mar Biotechnol (NY), 2007 Nov-Dec. PMID 17671813
    2. Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. England SJ, et al. Front Cell Dev Biol, 2017. PMID 28271061, Free PMC Article
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables chromatin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA replication IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in DNA-templated DNA replication IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in DNA-templated DNA replication ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in sister chromatid cohesion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    part_of MCM complex ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    mini-chromosome maintenance complex-binding protein
    Names
    MCM-binding protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_212578.1 → NP_997743.1  mini-chromosome maintenance complex-binding protein

      See identical proteins and their annotated locations for NP_997743.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044562
      Related
      ENSDARP00000130337.2, ENSDART00000168099.2
      Conserved Domains (1) summary
      pfam09739
      Location:36 → 616
      MCM_bind; Mini-chromosome maintenance replisome factor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      25535043..25548882 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068224922.1 → XP_068081023.1  mini-chromosome maintenance complex-binding protein isoform X2

      UniProtKB/TrEMBL
      A0A8M2B3P0

    2. XM_068224921.1 → XP_068081022.1  mini-chromosome maintenance complex-binding protein isoform X1

      UniProtKB/Swiss-Prot
      A8E7D0, Q803A6
      Related
      ENSDARP00000120704.1, ENSDART00000135788.3
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q803A6.2 GenPept UniProtKB/Swiss-Prot:Q803A6

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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