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    vtg3 vitellogenin 3, phosvitinless [ Danio rerio (zebrafish) ]

    Gene ID: 30518, updated on 9-Dec-2024

    Summary

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    Official Symbol
    vtg3provided by ZNC
    Official Full Name
    vitellogenin 3, phosvitinlessprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-991019-2
    See related
    Ensembl:ENSDARG00000016448 AllianceGenome:ZFIN:ZDB-GENE-991019-2
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    vg3; cb1001; wu:fb58g02; wu:fb59f05; wu:fb61d01
    Summary
    Predicted to enable lipid transporter activity. Acts upstream of or within cellular response to estrogen stimulus; hatching; and positive regulation of fertilization. Is expressed in several structures, including axis; digestive system; female organism; hatching gland; and sensory system. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See vtg3 in Genome Data Viewer
    Location:
    chromosome: 11
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 11 NC_007122.7 (7359713..7380693, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 11 NC_007122.6 (7349874..7370854, complement)

    Chromosome 11 - NC_007122.7Genomic Context describing neighboring genes Neighboring gene DIRAS family, GTP-binding RAS-like 1a Neighboring gene IFI30 lysosomal thiol reductase b Neighboring gene adhesion G protein-coupled receptor L4 Neighboring gene adhesion G protein-coupled receptor L2a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Effects of 17a-ethinylestradiol on the expression of three estrogen-responsive genes and cellular ultrastructure of liver and testes in male zebrafish. Islinger M, et al. Aquat Toxicol, 2003 Jan 24. PMID 12505378
    2. Ecotoxicogenomics to support ecological risk assessment: a case study with bisphenol A in fish. Villeneuve DL, et al. Environ Sci Technol, 2012 Jan 3. PMID 21786754
    3. Influence of multiwall carbon nanotubes on the toxicity of 17β-estradiol in the early life stages of zebrafish. Yan Z, et al. Environ Sci Pollut Res Int, 2018 Mar. PMID 29282666
    4. Microparticle formulations alter the toxicity of fenofibrate to the zebrafish Danio rerio embryo. Hering I, et al. Aquat Toxicol, 2021 May. PMID 33799113
    5. Inhibition of vitellogenin gene induction by 2,3,7,8-tetrachlorodibenzo-p-dioxin is mediated by aryl hydrocarbon receptor 2 (AHR2) in zebrafish (Danio rerio). Bugel SM, et al. Aquat Toxicol, 2013 Jan 15. PMID 23142599

    See all (63) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables lipid transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lipid transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nutrient reservoir activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in cellular response to estrogen stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within cellular response to estrogen stimulus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within hatching IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of fertilization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in response to estradiol IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    vitellogenin 3, phosvitinless
    Names
    phosvitinless vitellogenin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131265.1 → NP_571340.1  vitellogenin 3, phosvitinless precursor

      Status: VALIDATED

      Source sequence(s)
      CR678040, CU464206
      UniProtKB/TrEMBL
      A0A8M1P7D8, F1QQQ3
      Related
      ENSDARP00000094194.4, ENSDART00000103418.5
      Conserved Domains (3) summary
      pfam01347
      Location:24 → 592
      Vitellogenin_N; Lipoprotein amino terminal region
      pfam09172
      Location:626 → 912
      DUF1943; Domain of unknown function (DUF1943)
      pfam09175
      Location:1070 → 1238
      DUF1944; Domain of unknown function (DUF1944)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007122.7 Reference GRCz11 Primary Assembly

      Range
      7359713..7380693 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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