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    tial1 TIA1 cytotoxic granule-associated RNA binding protein-like 1 [ Danio rerio (zebrafish) ]

    Gene ID: 394107, updated on 9-Dec-2024

    Summary

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    Official Symbol
    tial1provided by ZNC
    Official Full Name
    TIA1 cytotoxic granule-associated RNA binding protein-like 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1547
    See related
    Ensembl:ENSDARG00000009525 AllianceGenome:ZFIN:ZDB-GENE-040426-1547
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:66130
    Summary
    Predicted to enable DNA binding activity and RNA binding activity. Orthologous to human TIAL1 (TIA1 cytotoxic granule associated RNA binding protein like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See tial1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (25472005..25484734, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (25341555..25354303, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene atonal bHLH transcription factor 7 Neighboring gene polycystic kidney disease 2-like 1 Neighboring gene BCL2 associated athanogene 3 Neighboring gene inositol polyphosphate-5-phosphatase F Neighboring gene minichromosome maintenance complex binding protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Identification and Expression Analysis of the Complete Family of Zebrafish pkd Genes. England SJ, et al. Front Cell Dev Biol, 2017. PMID 28271061, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC66130

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    nucleolysin TIAR

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_201132.1 → NP_957426.1  nucleolysin TIAR

      See identical proteins and their annotated locations for NP_957426.1

      Status: PROVISIONAL

      Source sequence(s)
      BC055501
      UniProtKB/TrEMBL
      A0A8N7V036, Q7SXQ1
      Related
      ENSDARP00000020234.5, ENSDART00000022799.7
      Conserved Domains (4) summary
      cd12616
      Location:9 → 89
      RRM1_TIAR; RNA recognition motif 1 in nucleolysin TIAR and similar proteins
      cd12617
      Location:95 → 174
      RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
      cd12620
      Location:204 → 276
      RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
      TIGR01661
      Location:7 → 270
      ELAV_HUD_SF; ELAV/HuD family splicing factor

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      25472005..25484734 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005156800.5 → XP_005156857.1  nucleolysin TIAR isoform X5

      UniProtKB/TrEMBL
      A0A8M2B2U9
      Conserved Domains (4) summary
      cd12616
      Location:9 → 89
      RRM1_TIAR; RNA recognition motif 1 in nucleolysin TIAR and similar proteins
      cd12617
      Location:95 → 184
      RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
      cd12620
      Location:214 → 286
      RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
      TIGR01661
      Location:7 → 280
      ELAV_HUD_SF; ELAV/HuD family splicing factor

    2. XM_005156799.5 → XP_005156856.1  nucleolysin TIAR isoform X4

      UniProtKB/TrEMBL
      A0A8M2B3J6
      Conserved Domains (4) summary
      COG0724
      Location:7 → 284
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12617
      Location:113 → 192
      RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
      cd12620
      Location:222 → 294
      RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
      cl17169
      Location:9 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    3. XM_009307302.4 → XP_009305577.1  nucleolysin TIAR isoform X2

      UniProtKB/TrEMBL
      A0A8M3AZ31
      Conserved Domains (4) summary
      COG0724
      Location:7 → 294
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12617
      Location:113 → 202
      RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
      cd12620
      Location:232 → 304
      RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
      cl17169
      Location:9 → 107
      RRM_SF; RNA recognition motif (RRM) superfamily

    4. XM_005156798.5 → XP_005156855.1  nucleolysin TIAR isoform X3

      UniProtKB/TrEMBL
      A0A8M2B3P8, E9QJJ0
      Related
      ENSDARP00000122887.1, ENSDART00000135321.3
      Conserved Domains (4) summary
      COG0724
      Location:7 → 285
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12617
      Location:114 → 193
      RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
      cd12620
      Location:223 → 295
      RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
      cl17169
      Location:9 → 108
      RRM_SF; RNA recognition motif (RRM) superfamily

    5. XM_005156797.5 → XP_005156854.1  nucleolysin TIAR isoform X1

      UniProtKB/TrEMBL
      A0A8M2B338
      Conserved Domains (4) summary
      COG0724
      Location:7 → 295
      RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
      cd12617
      Location:114 → 203
      RRM2_TIAR; RNA recognition motif 2 in nucleolysin TIAR and similar proteins
      cd12620
      Location:233 → 305
      RRM3_TIAR; RNA recognition motif 3 in nucleolysin TIAR and similar proteins
      cl17169
      Location:9 → 108
      RRM_SF; RNA recognition motif (RRM) superfamily

    6. XM_068212823.1 → XP_068068924.1  nucleolysin TIAR isoform X6

      UniProtKB/TrEMBL
      A0A8M2B2Y3, A0A8M3B810
    Nucleotide Protein Strain
    Heading Accession and Version

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