acss1 acyl-CoA synthetase short chain family member 1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: acss1provided by ZNC
Official Full Name: acyl-CoA synthetase short chain family member 1provided by ZNC
Primary source: ZFIN:ZDB-GENE-050320-139
See related: Ensembl:ENSDARG00000044142 AllianceGenome:ZFIN:ZDB-GENE-050320-139
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb395; sb:cb395; wu:fa05a10; wu:fc49f03; wu:fi28d10; zgc:113194; zgc:158738
Summary: Predicted to enable acetate-CoA ligase activity. Predicted to be involved in acetyl-CoA biosynthetic process. Predicted to act upstream of or within acetyl-CoA biosynthetic process from acetate and lipid metabolic process. Predicted to be active in mitochondrion. Is expressed in several structures, including blood; central nervous system; mesoderm; neural plate; and notochord. Orthologous to human ACSS1 (acyl-CoA synthetase short chain family member 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 17

Exon count:: 14

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	17	NC_007128.7 (25833947..25853915)
105	previous assembly	GRCz10 (GCF_000002035.5)	17	NC_007128.6 (25815556..25835524)

Chromosome 17 - NC_007128.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi28d10.x1 (e-PCR)
- UniSTS:197182

fc49f03 (e-PCR)
- UniSTS:189256

AW154548 (e-PCR)
- UniSTS:205904

fc29b01.y1 (e-PCR)
- UniSTS:193434

fa05a10.s1 (e-PCR)
- UniSTS:202208

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables AMP binding	IEA Inferred from Electronic Annotation more info
enables ATP binding	IEA Inferred from Electronic Annotation more info
enables acetate-CoA ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables acetate-CoA ligase activity	IEA Inferred from Electronic Annotation more info
enables ligase activity	IEA Inferred from Electronic Annotation more info
enables nucleotide binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in acetyl-CoA biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within acetyl-CoA biosynthetic process from acetate	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within lipid metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in mitochondrion	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: acetyl-coenzyme A synthetase 2-like, mitochondrial

Names: ACSS1A

NP_001074125.3

EC 6.2.1.13

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001080656.3 → NP_001074125.3 acetyl-coenzyme A synthetase 2-like, mitochondrial

Status: VALIDATED

Source sequence(s)

AL929023, BX000364, BX511070

UniProtKB/TrEMBL

A0A8M1ND09, F1QYS7

Related

ENSDARP00000044327.6, ENSDART00000044328.9

Conserved Domains (2) summary

cd05966
Location:66 → 672

ACS; Acetyl-CoA synthetase (also known as acetate-CoA ligase and acetyl-activating enzyme)

TIGR02188
Location:62 → 682

Ac_CoA_lig_AcsA; acetate--CoA ligase