sc:d189 sc:d189 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: sc:d189provided by ZNC
Official Full Name: sc:d189provided by ZNC
Primary source: ZFIN:ZDB-GENE-080303-11
See related: Ensembl:ENSDARG00000102858 AllianceGenome:ZFIN:ZDB-GENE-080303-11
Gene type: protein coding
RefSeq status: PREDICTED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable cell-cell adhesion mediator activity. Predicted to be involved in heterotypic cell-cell adhesion and negative regulation of neuroinflammatory response. Predicted to act upstream of or within negative regulation of macrophage activation and regulation of immune response. Predicted to be located in plasma membrane. Predicted to be active in axon; cell surface; and neuronal cell body. Is expressed in brain and telencephalon. [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 1

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	1	NC_007112.7 (35194453..35233115)
105	previous assembly	GRCz10 (GCF_000002035.5)	1	NC_007112.6 (34462469..34501082)

Chromosome 1 - NC_007112.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cell-cell adhesion mediator activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within negative regulation of macrophage activation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of immune response	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: uncharacterized protein LOC100002334

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001098260.1 → NP_001091730.1 uncharacterized protein LOC100002334 precursor

See identical proteins and their annotated locations for NP_001091730.1

Status: PREDICTED

Source sequence(s)

CU458946

UniProtKB/TrEMBL

A4JYM5

Related

ENSDARP00000141306.1, ENSDART00000165389.3

Conserved Domains (3) summary

cd05846
Location:148 → 244

Ig1_MRC-OX-2_like; First immunoglobulin (Ig) domain of rat MRC OX-2 antigen (also known as CD200) and similar proteins

smart00410
Location:142 → 243

IG_like; Immunoglobulin like

cl11960
Location:97 → 133

Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCz11 Primary Assembly

Genomic

NC_007112.7 Reference GRCz11 Primary Assembly

Range

35194453..35233115

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_005157078.5 → XP_005157135.1 uncharacterized protein LOC100002334 isoform X1

UniProtKB/TrEMBL

A0A0R4IVQ3, A0A8M2B3W3

Conserved Domains (3) summary

cd05846
Location:148 → 244

Ig1_MRC-OX-2_like; First immunoglobulin (Ig) domain of rat MRC OX-2 antigen (also known as CD200) and similar proteins

smart00410
Location:142 → 243

IG_like; Immunoglobulin like

cl11960
Location:97 → 133

Ig; Immunoglobulin domain