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    cacna1ha calcium channel, voltage-dependent, T type, alpha 1H subunit a [ Danio rerio (zebrafish) ]

    Gene ID: 560875, updated on 9-Dec-2024

    Summary

    Official Symbol
    cacna1haprovided by ZNC
    Official Full Name
    calcium channel, voltage-dependent, T type, alpha 1H subunit aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-130103-1
    See related
    Ensembl:ENSDARG00000060496 AllianceGenome:ZFIN:ZDB-GENE-130103-1
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    sb:cb648
    Summary
    Predicted to enable low voltage-gated calcium channel activity and voltage-gated sodium channel activity. Predicted to be involved in several processes, including metal ion transport; neuronal action potential; and positive regulation of calcium ion-dependent exocytosis. Predicted to act upstream of or within calcium ion transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of voltage-gated sodium channel complex. Predicted to be active in neuron projection. Is expressed in adaxial cell; diencephalon; heart; and retinal neural layer. Human ortholog(s) of this gene implicated in childhood absence epilepsy and primary hyperaldosteronism. Orthologous to human CACNA1H (calcium voltage-gated channel subunit alpha1 H). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See cacna1ha in Genome Data Viewer
    Location:
    chromosome: 3
    Exon count:
    35
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 3 NC_007114.7 (39759426..39953920)
    105 previous assembly GRCz10 (GCF_000002035.5) 3 NC_007114.6 (39711931..39810543)

    Chromosome 3 - NC_007114.7Genomic Context describing neighboring genes Neighboring gene epsin 2 Neighboring gene B9 protein domain 1 Neighboring gene coiled-coil domain containing 97 Neighboring gene LLGL scribble cell polarity complex component 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables monoatomic cation channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables monoatomic ion channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables voltage-gated calcium channel activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within calcium ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within calcium ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic ion transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of monoatomic ion channel complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of voltage-gated calcium channel complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    voltage-dependent T-type calcium channel subunit alpha-1H
    Names
    voltage-dependent T-type calcium channel subunit alpha-1H-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007114.7 Reference GRCz11 Primary Assembly

      Range
      39759426..39953920
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_009299685.4XP_009297960.2  voltage-dependent T-type calcium channel subunit alpha-1H

      UniProtKB/TrEMBL
      A0A8M3B162
      Related
      ENSDARP00000127548.1, ENSDART00000154869.3