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    lrrc15 leucine rich repeat containing 15 [ Danio rerio (zebrafish) ]

    Gene ID: 791200, updated on 9-Dec-2024

    Summary

    Official Symbol
    lrrc15provided by ZNC
    Official Full Name
    leucine rich repeat containing 15provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-031113-8
    See related
    Ensembl:ENSDARG00000070792 AllianceGenome:ZFIN:ZDB-GENE-031113-8
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb894; zgc:158286
    Summary
    Predicted to enable Roundabout binding activity and heparin binding activity. Predicted to be involved in axon guidance and negative chemotaxis. Predicted to be located in membrane. Is expressed in cardiovascular system; hematopoietic system; ventral mesoderm; and yolk syncytial layer. Orthologous to human LRRC15 (leucine rich repeat containing 15). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See lrrc15 in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (36459977..36463700)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (36482083..36485806)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene si:dkey-117a16.1 Neighboring gene Rh family, C glycoprotein, like 1 Neighboring gene uncharacterized LOC137495989 Neighboring gene uncharacterized LOC137490239 Neighboring gene hairy-related 6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables Roundabout binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables heparin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative chemotaxis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    leucine-rich repeat-containing protein 15

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001080682.1NP_001074151.1  leucine-rich repeat-containing protein 15 precursor

      See identical proteins and their annotated locations for NP_001074151.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129189
      UniProtKB/TrEMBL
      A1L1S0
      Related
      ENSDARP00000095023.3, ENSDART00000104248.4
      Conserved Domains (6) summary
      smart00013
      Location:2148
      LRRNT; Leucine rich repeat N-terminal domain
      cd00116
      Location:163253
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:171194
      LRR_RI; leucine-rich repeat [structural motif]
      pfam12799
      Location:241280
      LRR_4; Leucine Rich repeats (2 copies)
      pfam13855
      Location:170229
      LRR_8; Leucine rich repeat
      cl15307
      Location:418467
      TPKR_C2; Tyrosine-protein kinase receptor C2 Ig-like domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      36459977..36463700
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394657.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      105231..108953
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)