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    fastkd1 FAST kinase domains 1 [ Danio rerio (zebrafish) ]

    Gene ID: 100148546, updated on 9-Dec-2024

    Summary

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    Official Symbol
    fastkd1provided by ZNC
    Official Full Name
    FAST kinase domains 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1833
    See related
    Ensembl:ENSDARG00000056128 AllianceGenome:ZFIN:ZDB-GENE-040426-1833
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:77397
    Summary
    Predicted to enable RNA binding activity. Predicted to be involved in mitochondrial RNA processing and regulation of mitochondrial mRNA stability. Predicted to act upstream of or within phosphorylation. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial matrix and ribonucleoprotein granule. Orthologous to human FASTKD1 (FAST kinase domains 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See fastkd1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (48232545..48267437)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (48535150..48568766)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene phosphoglycerate dehydrogenase Neighboring gene cilia and flagella associated protein 210 Neighboring gene kelch-like family member 41a Neighboring gene Bardet-Biedl syndrome 5

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation. Oehlers SH, et al. Dev Comp Immunol, 2010 Mar. PMID 19941893
    2. Structure, evolution and expression of collagen XXVIII: Lessons from the zebrafish. Gebauer JM, et al. Matrix Biol, 2016 Jan. PMID 26235539
    3. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    5. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC77397

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables RNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mitochondrial RNA processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of mitochondrial mRNA stability IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within regulation of mitochondrial mRNA stability IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in mitochondrial matrix IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in ribonucleoprotein granule IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    FAST kinase domain-containing protein 1, mitochondrial

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205629.2 → NP_991192.2  FAST kinase domain-containing protein 1, mitochondrial

      Status: VALIDATED

      Source sequence(s)
      BX321905
      UniProtKB/TrEMBL
      A0A8M1PD17, E7F8W7
      Related
      ENSDARP00000118274.1, ENSDART00000141405.2
      Conserved Domains (3) summary
      smart00952
      Location:768 → 827
      RAP; This domain is found in various eukaryotic species, particularly in apicomplexans
      pfam06743
      Location:563 → 628
      FAST_1; FAST kinase-like protein, subdomain 1
      pfam08368
      Location:648 → 729
      FAST_2; FAST kinase-like protein, subdomain 2

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      48232545..48267437
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068223268.1 → XP_068079369.1  FAST kinase domain-containing protein 1, mitochondrial isoform X1

    Nucleotide Protein Strain
    Heading Accession and Version

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