ell2 elongation factor for RNA polymerase II 2 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ell2provided by ZNC
Official Full Name: elongation factor for RNA polymerase II 2provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-1717
See related: Ensembl:ENSDARG00000006251 AllianceGenome:ZFIN:ZDB-GENE-030131-1717
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: cb244; fb78f03; sb:cb244; im:3814960; wu:fb78f03
Summary: Predicted to enable cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription elongation by RNA polymerase II and snRNA transcription by RNA polymerase II. Predicted to act upstream of or within transcription elongation by RNA polymerase II and translational elongation. Predicted to be located in nucleus. Predicted to be part of transcription elongation factor complex. Is expressed in several structures, including anterior axial hypoblast; hatching gland; mesoderm; musculature system; and sensory system. Orthologous to human ELL2 (elongation factor for RNA polymerase II 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 21

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	21	NC_007132.7 (11749104..11774965)
105	previous assembly	GRCz10 (GCF_000002035.5)	21	NC_007132.6 (11656476..11682337)

Chromosome 21 - NC_007132.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

fi30d03.y1 (e-PCR)
- UniSTS:197238

fb78f03.x1 (e-PCR)
- UniSTS:191440

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables cis-regulatory region sequence-specific DNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables translation elongation factor activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in positive regulation of transcription elongation by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
involved_in snRNA transcription by RNA polymerase II	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translation	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within translational elongation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
part_of transcription elongation factor complex	IBA Inferred from Biological aspect of Ancestor more info
part_of transcription elongation factor complex	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: RNA polymerase II elongation factor ELL2

Names: elongation factor, RNA polymerase II 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001083812.2 → NP_001077281.2 RNA polymerase II elongation factor ELL2

Status: VALIDATED

Source sequence(s)

BC085600, BI673398, BM096368, BX511081, CT677237

UniProtKB/TrEMBL

A0A8M1NDW7, F1R2K7, Q5U3C7

Related

ENSDARP00000093185.3, ENSDART00000102408.5

Conserved Domains (2) summary

pfam07303
Location:552 → 647

Occludin_ELL; Occludin homology domain

pfam10390
Location:7 → 283

ELL; RNA polymerase II elongation factor ELL