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    osgepl1 O-sialoglycoprotein endopeptidase-like 1 [ Danio rerio (zebrafish) ]

    Gene ID: 368635, updated on 9-Dec-2024

    Summary

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    Official Symbol
    osgepl1provided by ZNC
    Official Full Name
    O-sialoglycoprotein endopeptidase-like 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030616-532
    See related
    Ensembl:ENSDARG00000000651 AllianceGenome:ZFIN:ZDB-GENE-030616-532
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    si:dz72b14.6
    Summary
    Predicted to enable N(6)-L-threonylcarbamoyladenine synthase activity. Predicted to be involved in tRNA threonylcarbamoyladenosine modification. Predicted to act upstream of or within tRNA processing. Predicted to be active in mitochondrion. Orthologous to human OSGEPL1 (O-sialoglycoprotein endopeptidase like 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See osgepl1 in Genome Data Viewer
    Location:
    chromosome: 9
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 9 NC_007120.7 (41040302..41045873)
    105 previous assembly GRCz10 (GCF_000002035.5) 9 NC_007120.6 (41238515..41244086)

    Chromosome 9 - NC_007120.7Genomic Context describing neighboring genes Neighboring gene si:ch211-3o3.7 Neighboring gene myostatin b Neighboring gene PMS1 homolog 1, mismatch repair system component Neighboring gene ORMDL sphingolipid biosynthesis regulator 1 Neighboring gene adenosine deaminase tRNA specific 3 Neighboring gene ankyrin and armadillo repeat containing Neighboring gene U5 spliceosomal RNA Neighboring gene zgc:136439 Neighboring gene asparagine synthetase domain containing 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. 15000 unique zebrafish EST clusters and their future use in microarray for profiling gene expression patterns during embryogenesis. Lo J, et al. Genome Res, 2003 Mar. PMID 12618376, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC123084

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables N(6)-L-threonylcarbamoyladenine synthase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables N(6)-L-threonylcarbamoyladenine synthase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    enables acyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within tRNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within tRNA threonylcarbamoyladenosine modification IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in tRNA threonylcarbamoyladenosine modification ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in mitochondrion ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial
    Names
    N6-L-threonylcarbamoyladenine synthase
    glycoprotease
    probable O-sialoglycoprotein endopeptidase 2
    probable tRNA threonylcarbamoyladenosine biosynthesis protein osgepl1
    t(6)A synthase
    NP_001005301.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005301.1 → NP_001005301.1  tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial

      See identical proteins and their annotated locations for NP_001005301.1

      Status: PROVISIONAL

      Source sequence(s)
      AL672217
      UniProtKB/Swiss-Prot
      Q32LQ3, Q8JFR7, Q8JFW3
      Related
      ENSDARP00000001156.8, ENSDART00000000693.9
      Conserved Domains (2) summary
      PRK09604
      Location:26 → 363
      PRK09604; UGMP family protein; Validated
      cl22532
      Location:27 → 157
      Carbam_trans_N; Carbamoyltransferase N-terminus

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007120.7 Reference GRCz11 Primary Assembly

      Range
      41040302..41045873
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q32LQ3.2 GenPept UniProtKB/Swiss-Prot:Q32LQ3

    Gene LinkOut

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