trim35-40 tripartite motif containing 35-40 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: trim35-40provided by ZNC
Official Full Name: tripartite motif containing 35-40provided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-6081
See related: Ensembl:ENSDARG00000042116 AllianceGenome:ZFIN:ZDB-GENE-030131-6081
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: fi33g05; wu:fi33g05; si:dkey-44k1.3
Summary: Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response. Predicted to act upstream of or within protein ubiquitination. Predicted to be active in cytoplasm. Orthologous to human TRIM35 (tripartite motif containing 35). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 25

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	25	NC_007136.7 (17495615..17503410, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	25	NC_007136.6 (17398872..17407072, complement)

Chromosome 25 - NC_007136.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables metal ion binding	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ubiquitin-protein transferase activity	IEA Inferred from Electronic Annotation more info
enables zinc ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in innate immune response	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within protein ubiquitination	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: uncharacterized protein LOC334149

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001386692.1 → NP_001373621.1 uncharacterized protein LOC334149

Status: VALIDATED

Source sequence(s)

AL844894, CU855816

UniProtKB/TrEMBL

A0A8M6YWM3, F1QSW1

Related

ENSDARP00000061725.4, ENSDART00000061726.5

Conserved Domains (5) summary

COG5432
Location:14 → 146

RAD18; RING-finger-containing E3 ubiquitin ligase [Signal transduction mechanisms]

TIGR04523
Location:111 → 224

Mplasa_alph_rch; helix-rich Mycoplasma protein

cd12893
Location:286 → 461

SPRY_PRY_TRIM35; PRY/SPRY domain in tripartite motif-containing protein 35 (TRIM35)

cd00162
Location:14 → 53

RING_Ubox; RING-HC finger (C3HC4-type) [structural motif]

cl17238
Location:12 → 56

RING_Ubox; The superfamily of RING finger (Really Interesting New Gene) domain and U-box domain