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    dcn decorin [ Danio rerio (zebrafish) ]

    Gene ID: 64698, updated on 9-Dec-2024

    Summary

    Official Symbol
    dcnprovided by ZNC
    Official Full Name
    decorinprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-010102-1
    See related
    Ensembl:ENSDARG00000012066 AllianceGenome:ZFIN:ZDB-GENE-010102-1
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    DC
    Summary
    Acts upstream of or within cartilage development; chondroitin sulfate proteoglycan metabolic process; and convergent extension involved in axis elongation. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in several structures, including cranial cartilage; epidermis; nervous system; pericardial region; and periderm. Human ortholog(s) of this gene implicated in breast carcinoma; congenital stromal corneal dystrophy; and high grade glioma. Orthologous to human DCN (decorin). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See dcn in Genome Data Viewer
    Location:
    chromosome: 4
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 4 NC_007115.7 (16368762..16406724, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 4 NC_007115.6 (16379786..16417748, complement)

    Chromosome 4 - NC_007115.7Genomic Context describing neighboring genes Neighboring gene keratocan Neighboring gene lumican Neighboring gene uncharacterized LOC103910437 Neighboring gene wu:fc23c09

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in extracellular region  
    is_active_in extracellular space  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_131697.1 → NP_571772.1  decorin precursor

      See identical proteins and their annotated locations for NP_571772.1

      Status: PROVISIONAL

      Source sequence(s)
      BC044206
      UniProtKB/TrEMBL
      Q803T1
      Related
      ENSDARP00000025940.8, ENSDART00000013085.9
      Conserved Domains (4) summary
      smart00013
      Location:66 → 97
      LRRNT; Leucine rich repeat N-terminal domain
      cd00116
      Location:233 → 326
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      sd00033
      Location:74 → 94
      LRR_RI; leucine-rich repeat [structural motif]
      pfam13855
      Location:233 → 293
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007115.7 Reference GRCz11 Primary Assembly

      Range
      16368762..16406724 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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