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    atp5if1b ATP synthase inhibitory factor subunit 1b [ Danio rerio (zebrafish) ]

    Gene ID: 558368, updated on 9-Dec-2024

    Summary

    Official Symbol
    atp5if1bprovided by ZNC
    Official Full Name
    ATP synthase inhibitory factor subunit 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050506-113
    See related
    Ensembl:ENSDARG00000044092 AllianceGenome:ZFIN:ZDB-GENE-050506-113
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    IF1 B; IF(1) B; atpif1b; im:6908140; zgc:153321; si:ch211-15d5.5; si:ch211-154e15.5
    Summary
    Predicted to enable ATPase binding activity; ATPase inhibitor activity; and protein homodimerization activity. Acts upstream of or within chordate embryonic development. Predicted to be active in mitochondrion. Is expressed in several structures, including blood; common myeloid progenitor; hatching gland; polster; and solid lens vesicle. Orthologous to human ATP5IF1 (ATP synthase inhibitory factor subunit 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See atp5if1b in Genome Data Viewer
    Location:
    chromosome: 17
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 17 NC_007128.7 (24613473..24614724)
    105 previous assembly GRCz10 (GCF_000002035.5) 17 NC_007128.6 (24595072..24596323)

    Chromosome 17 - NC_007128.7Genomic Context describing neighboring genes Neighboring gene dynein light chain Tctex-type 1a Neighboring gene zinc metallopeptidase, STE24 homolog Neighboring gene small nucleolar RNA Z195/SNORD33/SNORD32 family Neighboring gene ribosomal protein L13a Neighboring gene small nucleolar RNA SNORD50

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Markers

    Clone Names

    • MGC153321

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATPase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ATPase binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables ATPase inhibitor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables ATPase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables ATPase inhibitor activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables protein homodimerization activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within chordate embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in erythrocyte differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in erythrocyte differentiation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in heme biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in heme biosynthetic process ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within negative regulation of ATP-dependent activity IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in negative regulation of mitochondrial ATP synthesis coupled proton transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein homotetramerization ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ATPase inhibitor B, mitochondrial
    Names
    ATP synthase F1 subunit epsilon B
    ATPase inhibitory factor 1-like
    ATPase inhibitory factor 1b
    inhibitor of F(1)F(o)-ATPase B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001044859.1NP_001038324.1  ATPase inhibitor B, mitochondrial

      See identical proteins and their annotated locations for NP_001038324.1

      Status: PROVISIONAL

      Source sequence(s)
      BX005435
      UniProtKB/Swiss-Prot
      Q0P476, Q1LYB6
      Related
      ENSDARP00000064737.5, ENSDART00000064738.6
      Conserved Domains (1) summary
      pfam04568
      Location:3682
      IATP; Mitochondrial ATPase inhibitor, IATP

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007128.7 Reference GRCz11 Primary Assembly

      Range
      24613473..24614724
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394990.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      175438..176701
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)