ywhaz tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: ywhazprovided by ZNC
Official Full Name: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptideprovided by ZNC
Primary source: ZFIN:ZDB-GENE-030131-8554
See related: Ensembl:ENSDARG00000032575 AllianceGenome:ZFIN:ZDB-GENE-030131-8554
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: ywhai; fb14h09; zgc:55807; wu:fb05g08; wu:fb14h09
Summary: Predicted to be involved in protein localization and signal transduction. Predicted to be active in cytoplasm. Is expressed in several structures, including EVL; epidermis; nervous system; periderm; and tail bud. Orthologous to human YWHAZ (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs: all
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Genomic context

Location:: chromosome: 19

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	19	NC_007130.7 (12164410..12193718, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	19	NC_007130.6 (12244882..12274190, complement)

Chromosome 19 - NC_007130.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish.
Title: Deficiency of the ywhaz gene, involved in neurodevelopmental disorders, alters brain activity and behaviour in zebrafish.

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General gene information

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Markers

fj91f04.x1 (e-PCR)
- UniSTS:200313

fb14h09.x1 (e-PCR)
- UniSTS:202938

fb05g08.x1 (e-PCR)
- UniSTS:202707

AI330960 (e-PCR)
- UniSTS:206811

Gene Ontology Provided by ZFIN

Process	Evidence Code	Pubs
involved_in protein localization	IBA Inferred from Biological aspect of Ancestor more info
involved_in signal transduction	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: 14-3-3 protein zeta/delta

Names: tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, iota polypeptide

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.