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    trim109 tripartite motif containing 109 [ Danio rerio (zebrafish) ]

    Gene ID: 723998, updated on 9-Dec-2024

    Summary

    Official Symbol
    trim109provided by ZNC
    Official Full Name
    tripartite motif containing 109provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-060616-101
    See related
    Ensembl:ENSDARG00000062429 AllianceGenome:ZFIN:ZDB-GENE-060616-101
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    cb336; sb:cb336; zgc:136894
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in innate immune response. Predicted to be active in cytoplasm. Is expressed in adaxial cell; musculature system; myotome; and somite. [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See trim109 in Genome Data Viewer
    Location:
    chromosome: 16
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 16 NC_007127.7 (14064397..14074594, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 16 NC_007127.6 (14174277..14184474, complement)

    Chromosome 16 - NC_007127.7Genomic Context describing neighboring genes Neighboring gene farnesyl diphosphate synthase (farnesyl pyrophosphate synthetase, dimethylallyltranstransferase, geranyltranstransferase) Neighboring gene RUN and SH3 domain containing 1 Neighboring gene zinc finger protein 420-like Neighboring gene ash1 (absent, small, or homeotic)-like (Drosophila) pseudogene

    Genomic regions, transcripts, and products

    General gene information

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables ubiquitin protein ligase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in innate immune response IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    tripartite motif containing 109

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001045303.1NP_001038768.1  tripartite motif containing 109

      See identical proteins and their annotated locations for NP_001038768.1

      Status: PROVISIONAL

      Source sequence(s)
      BC117661
      UniProtKB/TrEMBL
      A0A8N1YXR2, Q1ECU9
      Related
      ENSDARP00000084667.5, ENSDART00000090234.6
      Conserved Domains (4) summary
      cd00021
      Location:105142
      BBOX; B-Box-type zinc finger; zinc binding domain (CHC3H2); often present in combination with other motifs, like RING zinc finger, NHL motif, coiled-coil or RFP domain in functionally unrelated proteins, most likely mediating protein-protein interaction.
      cd00162
      Location:1053
      RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
      cl02614
      Location:342492
      SPRY; SPRY domain
      cl21528
      Location:162233
      Lipocalin; Lipocalin / cytosolic fatty-acid binding protein family

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007127.7 Reference GRCz11 Primary Assembly

      Range
      14064397..14074594 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)