s100a1 S100 calcium binding protein A1 [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: s100a1provided by ZNC
Official Full Name: S100 calcium binding protein A1provided by ZNC
Primary source: ZFIN:ZDB-GENE-040916-1
See related: Ensembl:ENSDARG00000015543 AllianceGenome:ZFIN:ZDB-GENE-040916-1
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Summary: Predicted to enable calcium ion binding activity and calcium-dependent protein binding activity. Predicted to act upstream of or within regulation of heart contraction. Predicted to be located in mitochondrion and sarcoplasmic reticulum. Predicted to be active in cytoplasm. Is expressed in several structures, including gill; gut; hematopoietic system; olfactory epithelium; and renal system. Orthologous to human S100A1 (S100 calcium binding protein A1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 16

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	16	NC_007127.7 (29385560..29387215, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	16	NC_007127.6 (29450932..29452592, complement)

Chromosome 16 - NC_007127.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables calcium ion binding	IBA Inferred from Biological aspect of Ancestor more info
enables calcium ion binding	IEA Inferred from Electronic Annotation more info
enables calcium-dependent protein binding	IBA Inferred from Biological aspect of Ancestor more info
enables metal ion binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within regulation of heart contraction	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
located_in sarcoplasmic reticulum	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein S100-A1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001089351.2 → NP_001082820.1 protein S100-A1

See identical proteins and their annotated locations for NP_001082820.1

Status: VALIDATED

Source sequence(s)

EH492790, EH575828

UniProtKB/TrEMBL

A3KH13, F5HN08

Related

ENSDARP00000123790.1, ENSDART00000148787.2

Conserved Domains (1) summary

cd05025
Location:2 → 93

S-100A1; S-100A1: S-100A1 domain found in proteins similar to S100A1. S100A1 is a calcium-binding protein belonging to a large S100 vertebrate-specific protein family within the EF-hand superfamily of calcium-binding proteins. Note that the S-100 hierarchy, to ...