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    ywhaba tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a [ Danio rerio (zebrafish) ]

    Gene ID: 323055, updated on 9-Dec-2024

    Summary

    Official Symbol
    ywhabaprovided by ZNC
    Official Full Name
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-6583
    See related
    Ensembl:ENSDARG00000013078 AllianceGenome:ZFIN:ZDB-GENE-030131-6583
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    ywhab1; fb80c08; fk41f08; wu:fb80c08; wu:fd11d01; wu:fk41f08
    Summary
    Acts upstream of or within phagocytosis, engulfment. Predicted to be active in cytoplasm. Is expressed in several structures, including nervous system; optic vesicle; otic vesicle; solid lens vesicle; and tail bud. Orthologous to human YWHAB (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See ywhaba in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (52212574..52222955)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (52212575..52222956)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene actin binding Rho activating protein a Neighboring gene regulating synaptic membrane exocytosis 4 Neighboring gene translocase of outer mitochondrial membrane 34 Neighboring gene cytochrome c oxidase subunit 6C

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Process Evidence Code Pubs
    acts_upstream_of_or_within phagocytosis, engulfment IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    14-3-3 protein beta/alpha-A
    Names
    14-3-3 protein beta/alpha-1
    tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082798.1NP_001076267.1  14-3-3 protein beta/alpha-A

      See identical proteins and their annotated locations for NP_001076267.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133863
      UniProtKB/Swiss-Prot
      A3KNI9, Q5PRD0
      Related
      ENSDARP00000027118.8, ENSDART00000025940.10
      Conserved Domains (1) summary
      cd10022
      Location:2230
      14-3-3_beta_zeta; 14-3-3 beta and zeta isoforms of 14-3-3 protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      52212574..52222955
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)