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    paip2b poly(A) binding protein interacting protein 2B [ Danio rerio (zebrafish) ]

    Gene ID: 393739, updated on 9-Dec-2024

    Summary

    Official Symbol
    paip2bprovided by ZNC
    Official Full Name
    poly(A) binding protein interacting protein 2Bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1736
    See related
    Ensembl:ENSDARG00000008706 AllianceGenome:ZFIN:ZDB-GENE-040426-1736
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:73265
    Summary
    Predicted to enable translation repressor activity. Predicted to be involved in negative regulation of translation. Predicted to act upstream of or within negative regulation of translational initiation. Predicted to be active in cytoplasm. Orthologous to human PAIP2B (poly(A) binding protein interacting protein 2B). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See paip2b in Genome Data Viewer
    Location:
    chromosome: 1
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 1 NC_007112.7 (41465771..41471621)
    105 previous assembly GRCz10 (GCF_000002035.5) 1 NC_007112.6 (40762984..40768834)

    Chromosome 1 - NC_007112.7Genomic Context describing neighboring genes Neighboring gene si:ch211-89o9.4 Neighboring gene transfer RNA glutamic acid (anticodon CUC) Neighboring gene docking protein 1a Neighboring gene si:ch211-89o9.6

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC73265

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables mRNA regulatory element binding translation repressor activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables translation repressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in negative regulation of translation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within negative regulation of translational initiation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    polyadenylate-binding protein-interacting protein 2B
    Names
    paip2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_200766.1NP_957060.1  polyadenylate-binding protein-interacting protein 2B

      See identical proteins and their annotated locations for NP_957060.1

      Status: PROVISIONAL

      Source sequence(s)
      BC059597
      UniProtKB/TrEMBL
      Q6PBS9
      Related
      ENSDARP00000010658.5, ENSDART00000010211.7
      Conserved Domains (1) summary
      pfam07145
      Location:113130
      PAM2; Ataxin-2 C-terminal region

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007112.7 Reference GRCz11 Primary Assembly

      Range
      41465771..41471621
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)