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    sfr1 SWI5-dependent homologous recombination repair protein 1 [ Danio rerio (zebrafish) ]

    Gene ID: 568747, updated on 9-Dec-2024

    Summary

    Official Symbol
    sfr1provided by ZNC
    Official Full Name
    SWI5-dependent homologous recombination repair protein 1provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-070410-27
    See related
    Ensembl:ENSDARG00000021974 AllianceGenome:ZFIN:ZDB-GENE-070410-27
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    meir5; zgc:162162
    Summary
    Predicted to enable nuclear receptor coactivator activity. Predicted to be involved in double-strand break repair via homologous recombination and positive regulation of DNA-templated transcription. Predicted to act upstream of or within DNA repair. Predicted to be located in nucleus. Predicted to be part of Swi5-Sfr1 complex. Orthologous to human SFR1 (SWI5 dependent homologous recombination repair protein 1). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See sfr1 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (24742724..24745263, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (24612274..24614708, complement)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene sperm flagellar 1 Neighboring gene ER lipid raft associated 1 Neighboring gene cilia and flagella associated protein 43 Neighboring gene collagen, type XVII, alpha 1b Neighboring gene STE20-like kinase a

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    General gene information

    Clone Names

    • MGC162162

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nuclear receptor coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables nuclear receptor coactivator activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA repair IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in double-strand break repair via homologous recombination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within double-strand break repair via homologous recombination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in double-strand break repair via homologous recombination ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in positive regulation of DNA-templated transcription IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Swi5-Sfr1 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Swi5-Sfr1 complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of Swi5-Sfr1 complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    swi5-dependent recombination DNA repair protein 1 homolog
    Names
    MEI5 meiotic recombination protein homolog
    SWI5-dependent recombination repair 1
    meiosis protein 5 homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001082860.1NP_001076329.1  swi5-dependent recombination DNA repair protein 1 homolog

      See identical proteins and their annotated locations for NP_001076329.1

      Status: PROVISIONAL

      Source sequence(s)
      BC133892
      Related
      ENSDARP00000037070.6, ENSDART00000031564.8
      Conserved Domains (1) summary
      pfam10376
      Location:21192
      Mei5; Double-strand recombination repair protein

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      24742724..24745263 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_068212909.1XP_068069010.1  swi5-dependent recombination DNA repair protein 1 homolog isoform X1

      UniProtKB/Swiss-Prot
      A3KNK5, B7ZD04