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    rgs5a regulator of G protein signaling 5a [ Danio rerio (zebrafish) ]

    Gene ID: 573765, updated on 9-Dec-2024

    Summary

    Official Symbol
    rgs5aprovided by ZNC
    Official Full Name
    regulator of G protein signaling 5aprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030131-7570
    See related
    Ensembl:ENSDARG00000002644 AllianceGenome:ZFIN:ZDB-GENE-030131-7570
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    rgs5; fj30h05; zgc:64006; wu:fj30h05
    Summary
    Predicted to be located in cytoplasm and membrane. Is expressed in bulbus arteriosus; cranial blood vessel; eye; and trunk vasculature. Human ortholog(s) of this gene implicated in colorectal adenocarcinoma and essential hypertension. Orthologous to human RGS5 (regulator of G protein signaling 5). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
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    Genomic context

    See rgs5a in Genome Data Viewer
    Location:
    chromosome: 6
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 6 NC_007117.7 (35387365..35401282, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 6 NC_007117.6 (35404105..35417969, complement)

    Chromosome 6 - NC_007117.7Genomic Context describing neighboring genes Neighboring gene nitric oxide synthase 1 (neuronal) adaptor protein a Neighboring gene regulator of G protein signaling 4 Neighboring gene regulator of G protein signaling 16 Neighboring gene regulator of G protein signaling 8

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Clone Names

    • MGC64006, MGC174043

    Gene Ontology Provided by ZFIN

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    regulator of G-protein signaling 5a
    Names
    regulator of G-protein signaling 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_199962.2NP_956256.1  regulator of G-protein signaling 5a

      See identical proteins and their annotated locations for NP_956256.1

      Status: VALIDATED

      Source sequence(s)
      CR385065, EH446144
      UniProtKB/TrEMBL
      A0A2R8QNY6, F6P1C0, Q7T2D3
      Related
      ENSDARP00000108854.2, ENSDART00000127612.4
      Conserved Domains (1) summary
      cl02565
      Location:66179
      RGS; Regulator of G protein signaling (RGS) domain superfamily

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007117.7 Reference GRCz11 Primary Assembly

      Range
      35387365..35401282 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Reference GRCz11 ALT_DRER_TU_1

    Genomic

    1. NW_018394656.1 Reference GRCz11 ALT_DRER_TU_1

      Range
      142909..156513 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)