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    slc38a6 solute carrier family 38 member 6 [ Danio rerio (zebrafish) ]

    Gene ID: 336741, updated on 9-Dec-2024

    Summary

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    Official Symbol
    slc38a6provided by ZNC
    Official Full Name
    solute carrier family 38 member 6provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-050522-51
    See related
    Ensembl:ENSDARG00000054312 AllianceGenome:ZFIN:ZDB-GENE-050522-51
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    wu:fa94c12; wu:fb95f08; zgc:110611
    Summary
    Predicted to enable L-glutamine transmembrane transporter activity. Predicted to be involved in amino acid transmembrane transport and glutamine transport. Predicted to act upstream of or within amino acid transport and sodium ion transport. Predicted to be located in membrane. Predicted to be active in plasma membrane. Orthologous to human SLC38A6 (solute carrier family 38 member 6). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See slc38a6 in Genome Data Viewer
    Location:
    chromosome: 13
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 13 NC_007124.7 (31687978..31707866)
    105 previous assembly GRCz10 (GCF_000002035.5) 13 NC_007124.6 (31557497..31577435)

    Chromosome 13 - NC_007124.7Genomic Context describing neighboring genes Neighboring gene MNAT1 component of CDK activating kinase Neighboring gene tRNA methyltransferase 5 Neighboring gene protein kinase C, eta, a Neighboring gene hypoxia inducible factor 1 subunit alpha a

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Evolutionary comparison reveals that diverging CTCF sites are signatures of ancestral topological associating domains borders. Gómez-Marín C, et al. Proc Natl Acad Sci U S A, 2015 Jun 16. PMID 26034287, Free PMC Article
    2. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article
    3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article
    4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
    5. Gene evolution and gene expression after whole genome duplication in fish: the PhyloFish database. Pasquier J, et al. BMC Genomics, 2016 May 18. PMID 27189481, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables L-glutamine transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in amino acid transmembrane transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within amino acid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in glutamine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within monoatomic ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within sodium ion transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in plasma membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    probable sodium-coupled neutral amino acid transporter 6
    Names
    Na(+)-coupled neutral amino acid transporter 6

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001020472.1 → NP_001018308.1  probable sodium-coupled neutral amino acid transporter 6

      See identical proteins and their annotated locations for NP_001018308.1

      Status: PROVISIONAL

      Source sequence(s)
      BC095334
      UniProtKB/Swiss-Prot
      Q503G8
      Related
      ENSDARP00000070951.4, ENSDART00000076479.6
      Conserved Domains (2) summary
      COG0814
      Location:37 → 442
      SdaC; Amino acid permease [Amino acid transport and metabolism]
      cl00456
      Location:36 → 443
      SLC5-6-like_sbd; Solute carrier families 5 and 6-like; solute binding domain

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007124.7 Reference GRCz11 Primary Assembly

      Range
      31687978..31707866
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q503G8.1 GenPept UniProtKB/Swiss-Prot:Q503G8

    Gene LinkOut

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