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    cstf3 cleavage stimulation factor, 3' pre-RNA, subunit 3 [ Danio rerio (zebrafish) ]

    Gene ID: 406326, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cstf3provided by ZNC
    Official Full Name
    cleavage stimulation factor, 3' pre-RNA, subunit 3provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-040426-1997
    See related
    Ensembl:ENSDARG00000018904 AllianceGenome:ZFIN:ZDB-GENE-040426-1997
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    zgc:56028; wu:fa99c02; wu:fb18b09
    Summary
    Predicted to enable mRNA binding activity. Predicted to be involved in RNA 3'-end processing. Predicted to act upstream of or within mRNA 3'-end processing. Predicted to be active in nucleus. Orthologous to human CSTF3 (cleavage stimulation factor subunit 3). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    human mouse all
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    Genomic context

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    See cstf3 in Genome Data Viewer
    Location:
    chromosome: 18
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCz11 (GCF_000002035.6) 18 NC_007129.7 (45734290..45761868, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 18 NC_007129.6 (45737464..45765042, complement)

    Chromosome 18 - NC_007129.7Genomic Context describing neighboring genes Neighboring gene glutamine and serine rich 1 Neighboring gene DEP domain containing 7, paralog a Neighboring gene uncharacterized LOC606627 Neighboring gene si:dkey-34o23.3

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

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    Related articles in PubMed

    1. Regulatory back-up circuit of medaka Wt1 co-orthologs ensures PGC maintenance. Klüver N, et al. Dev Biol, 2009 Jan 1. PMID 18992736
    2. Evolution of the vertebrate Pax4/6 class of genes with focus on its novel member, the Pax10 gene. Feiner N, et al. Genome Biol Evol, 2014 Jun 19. PMID 24951566, Free PMC Article
    3. Online automated in vivo zebrafish phosphoproteomics: from large-scale analysis down to a single embryo. Lemeer S, et al. J Proteome Res, 2008 Apr. PMID 18307296
    4. Genetic landscape of T cells identifies synthetic lethality for T-ALL. O'Meara CP, et al. Commun Biol, 2021 Oct 20. PMID 34671088, Free PMC Article
    5. TIF1gamma controls erythroid cell fate by regulating transcription elongation. Bai X, et al. Cell, 2010 Jul 9. PMID 20603019, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables mRNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within RNA processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within mRNA 3'-end processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    cleavage stimulation factor subunit 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_213053.2 → NP_998218.2  cleavage stimulation factor subunit 3

      Status: VALIDATED

      Source sequence(s)
      BC045871, DT871999, EB848641, EH433088, EH459092
      UniProtKB/TrEMBL
      A0A8M1PEH9, F1QIB2, Q7ZVG5
      Related
      ENSDARP00000003969.7, ENSDART00000025423.9
      Conserved Domains (4) summary
      smart00386
      Location:45 → 77
      HAT; HAT (Half-A-TPR) repeats
      COG5107
      Location:1 → 515
      RNA14; Pre-mRNA 3'-end processing (cleavage and polyadenylation) factor [RNA processing and modification]
      sd00006
      Location:31 → 60
      TPR; TPR repeat [structural motif]
      pfam05843
      Location:375 → 648
      Suf; Suppressor of forked protein (Suf)

    RefSeqs of Annotated Genomes: GCF_000002035.6-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007129.7 Reference GRCz11 Primary Assembly

      Range
      45734290..45761868 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version

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