pfn2b profilin 2b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: pfn2bprovided by ZNC
Official Full Name: profilin 2bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040115-4
See related: Ensembl:ENSDARG00000003952 AllianceGenome:ZFIN:ZDB-GENE-040115-4
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: pfn2; wu:fb01g08; wu:fb54f09; wu:fd58f06
Summary: Predicted to enable actin binding activity. Predicted to be involved in positive regulation of actin filament bundle assembly and regulation of actin filament polymerization. Predicted to act upstream of or within actin cytoskeleton organization. Predicted to be active in cytoplasm. Is expressed in artery; axial vasculature; and vein. Orthologous to human PFN2 (profilin 2). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: all
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Genomic context

Location:: chromosome: 22

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (35179575..35194201, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (35203826..35218474, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

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General gene information

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Markers

fd58f06.x1 (e-PCR)
- UniSTS:195726

fb01g08.x1 (e-PCR)
- UniSTS:202659

AI477026 (e-PCR)
- UniSTS:206535

Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables actin binding	IBA Inferred from Biological aspect of Ancestor more info
enables actin binding	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within actin cytoskeleton organization	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of actin filament bundle assembly	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of actin filament polymerization	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: profilin-2

Names: profilin 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.