mid1ip1b MID1 interacting protein 1b [Danio rerio (zebrafish)] - Gene

Summary

Official Symbol: mid1ip1bprovided by ZNC
Official Full Name: MID1 interacting protein 1bprovided by ZNC
Primary source: ZFIN:ZDB-GENE-040426-1720
See related: Ensembl:ENSDARG00000019302 AllianceGenome:ZFIN:ZDB-GENE-040426-1720
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Danio rerio
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
Also known as: zgc:73223
Summary: Enables gamma-tubulin complex binding activity. Involved in microtubule organizing center localization. Acts upstream of or within with a positive effect on epithelial tube formation. Predicted to be located in cytoplasm; microtubule; and nucleus. Predicted to be active in cytosol. Is expressed in several structures, including alar plate midbrain region; digestive system; ectoderm; hatching gland; and nervous system. Orthologous to human MID1IP1 (MID1 interacting protein 1). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 22

Exon count:: 2

Annotation release	Status	Assembly	Chr	Location
RS_2024_08	current	GRCz11 (GCF_000002035.6)	22	NC_007133.7 (11437389..11438602, complement)
105	previous assembly	GRCz10 (GCF_000002035.5)	22	NC_007133.6 (11407707..11408818, complement)

Chromosome 22 - NC_007133.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
BioProject: PRJEB1986
Analysis date: Fri Dec 8 19:48:10 2017

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Mid1ip1b has a close interaction with gamma-tubulin protein and modulates lumen opening of the neural tube, gut, intestine, and kidney of zebrafish.
Title: Mid1ip1b modulates apical reorientation of non-centrosomal microtubule organizing center in epithelial cells.

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General gene information

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Gene Ontology Provided by ZFIN

Function	Evidence Code	Pubs
enables gamma-tubulin complex binding	IDA Inferred from Direct Assay more info	PubMed

Process	Evidence Code	Pubs
acts_upstream_of_or_within_positive_effect epithelial tube formation	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in microtubule organizing center localization	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of lipid biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
is_active_in cytosol	IBA Inferred from Biological aspect of Ancestor more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: mid1-interacting protein 1-B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.