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    PGP1 phosphatidylglycerolphosphate synthase 1 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 818514, updated on 18-Sep-2024

    Summary

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    Official Symbol
    PGP1
    Official Full Name
    phosphatidylglycerolphosphate synthase 1
    Primary source
    TAIR:AT2G39290
    Locus tag
    AT2G39290
    See related
    Araport:AT2G39290
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    PGPS1; PGS1; phosphatidylglycerolphosphate synthase 1; PHOSPHATIDYLGLYCEROLPHOSPHATE SYNTHASE 1; T16B24.7; T16B24_7
    Summary
    Encodes a phosphatidylglycerolphosphate synthase 2C which is dual-targeted into chloroplasts and mitochondria. Mutant plants have mutant chloroplasts but normal mitochondria.
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    Genomic context

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    See PGP1 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    6
    Sequence:
    Chromosome: 2; NC_003071.7 (16407135..16409156)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene P-loop containing nucleoside triphosphate hydrolases superfamily protein Neighboring gene ncRNA Neighboring gene Ypt/Rab-GAP domain of gyp1p superfamily protein Neighboring gene CAP-gly domain linker Neighboring gene jacalin-related lectin 22

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Multiple Impacts of Loss of Plastidic Phosphatidylglycerol Biosynthesis on Photosynthesis during Seedling Growth of Arabidopsis. Kobayashi K, et al. Front Plant Sci, 2016. PMID 27047516, Free PMC Article
    2. Arabidopsis phosphatidylglycerophosphate synthase 1 is essential for chloroplast differentiation, but is dispensable for mitochondrial function. Babiychuk E, et al. Plant J, 2003 Mar. PMID 12609031
    3. The pgp1 mutant locus of Arabidopsis encodes a phosphatidylglycerolphosphate synthase with impaired activity. Xu C, et al. Plant Physiol, 2002 Jun. PMID 12068104, Free PMC Article
    4. Phosphatidylglycerophosphate synthases from Arabidopsis thaliana. Müller F, et al. FEBS Lett, 2001 Dec 7. PMID 11741606
    5. Proteomics of the chloroplast envelope membranes from Arabidopsis thaliana. Ferro M, et al. Mol Cell Proteomics, 2003 May. PMID 12766230

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_129486.5

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables manganese ion binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in phosphatidylglycerol biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within phosphatidylinositol biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within phospholipid biosynthetic process IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within phospholipid biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thylakoid membrane organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Golgi apparatus HDA PubMed 
    located_in chloroplast HDA PubMed 
    located_in chloroplast IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in chloroplast ISS
    Inferred from Sequence or Structural Similarity
    more info
    		 PubMed 
    located_in chloroplast envelope HDA PubMed 
    located_in mitochondrion IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    phosphatidylglycerolphosphate synthase 1
    NP_181461.1
    • phosphatidylglycerolphosphate synthase 1 (PGP1); FUNCTIONS IN: CDP-alcohol phosphatidyltransferase activity, CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase activity; INVOLVED IN: phosphatidylinositol biosynthetic process, phospholipid biosynthetic process; LOCATED IN: mitochondrion, chloroplast, chloroplast envelope; EXPRESSED IN: 22 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (InterPro:IPR004570), CDP-alcohol phosphatidyltransferase (InterPro:IPR000462); BEST Arabidopsis thaliana protein match is: phosphatidylglycerolphosphate synthase 2 (TAIR:AT3G55030.1); Has 7695 Blast hits to 7695 proteins in 2371 species: Archae - 0; Bacteria - 5013; Metazoa - 112; Fungi - 127; Plants - 109; Viruses - 0; Other Eukaryotes - 2334 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      16407135..16409156
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_129486.5 → NP_181461.1  phosphatidylglycerolphosphate synthase 1 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_181461.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O80952, Q67ZP8
      UniProtKB/TrEMBL
      A0A178VXZ6, A0A5S9X5X1, A0A7G2ECS3
      Conserved Domains (1) summary
      cl00453
      Location:103 → 296
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O80952.1

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