U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    ABCG32 pleiotropic drug resistance 4 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817232, updated on 18-Sep-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    ABCG32
    Official Full Name
    pleiotropic drug resistance 4
    Primary source
    TAIR:AT2G26910
    Locus tag
    AT2G26910
    See related
    Araport:AT2G26910
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtABCG32; ATP-binding cassette G32; ATPDR4; F12C20.5; F12C20_5; PDR4; PEC1; PERMEABLE CUTICLE 1; pleiotropic drug resistance 4; PLEIOTROPIC DRUG RESISTANCE 4
    Summary
    Encodes a member of the PLEIOTROPIC DRUG RESISTANCE family of ATP binding cassette transporters. Required for the formation of a functional cuticle.
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See ABCG32 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    24
    Sequence:
    Chromosome: 2; NC_003071.7 (11481326..11488270)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene DNAJ heat shock N-terminal domain-containing protein Neighboring gene Sodium Bile acid symporter family Neighboring gene Ubiquitin-associated/translation elongation factor EF1B protein Neighboring gene 4-(cytidine 5'-phospho)-2-C-methyl-D-erithritol kinase Neighboring gene C2H2-type zinc finger family protein

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. The ABCG transporter PEC1/ABCG32 is required for the formation of the developing leaf cuticle in Arabidopsis. Fabre G, et al. New Phytol, 2016 Jan. PMID 26406899
    2. A member of the PLEIOTROPIC DRUG RESISTANCE family of ATP binding cassette transporters is required for the formation of a functional cuticle in Arabidopsis. Bessire M, et al. Plant Cell, 2011 May. PMID 21628525, Free PMC Article
    3. Proteome-wide screens for small ubiquitin-like modifier (SUMO) substrates identify Arabidopsis proteins implicated in diverse biological processes. Elrouby N, et al. Proc Natl Acad Sci U S A, 2010 Oct 5. PMID 20855607, Free PMC Article
    4. Global Analysis of Membrane-associated Protein Oligomerization Using Protein Correlation Profiling. McBride Z, et al. Mol Cell Proteomics, 2017 Nov. PMID 28887381, Free PMC Article
    5. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. PEC1/ABCG32 transport activity affects cutin composition and cuticle structure in a specific and non-redundant fashion.
      Title: The ABCG transporter PEC1/ABCG32 is required for the formation of the developing leaf cuticle in Arabidopsis.
    2. ABCG32 is involved in the formation of the cuticular layer of the cell wall, most likely by exporting particular cutin precursors from the epidermal cell.
      Title: A member of the PLEIOTROPIC DRUG RESISTANCE family of ATP binding cassette transporters is required for the formation of a functional cuticle in Arabidopsis.
    Submit: New GeneRIF Correction

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    NM_128248.2

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATP hydrolysis activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ATPase-coupled transmembrane transporter activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cutin transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in peroxisome HDA PubMed 
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    pleiotropic drug resistance 4
    NP_180259.1
    • pleiotropic drug resistance 4 (PDR4); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: drug transmembrane transport; LOCATED IN: membrane; EXPRESSED IN: 23 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), Plant PDR ABC transporter associated (InterPro:IPR013581), ABC-2 type transporter (InterPro:IPR013525); BEST Arabidopsis thaliana protein match is: pleiotropic drug resistance 12 (TAIR:AT1G15520.1); Has 401729 Blast hits to 274780 proteins in 3990 species: Archae - 7906; Bacteria - 327119; Metazoa - 10011; Fungi - 7454; Plants - 6269; Viruses - 4; Other Eukaryotes - 42966 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      11481326..11488270
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128248.2 → NP_180259.1  pleiotropic drug resistance 4 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180259.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O81016
      UniProtKB/TrEMBL
      A0A178VNA5, A0A5S9X1T8, A0A7G2E998
      Conserved Domains (1) summary
      PLN03140
      Location:3 → 1420
      PLN03140; ABC transporter G family member; Provisional
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O81016.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools