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    ABCC13 multidrug resistance-associated protein 11 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 815414, updated on 18-Sep-2024

    Summary

    Official Symbol
    ABCC13
    Official Full Name
    multidrug resistance-associated protein 11
    Primary source
    TAIR:AT2G07680
    Locus tag
    AT2G07680
    See related
    Araport:AT2G07680
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    AtABCC13; ATMRP11; ATP-binding cassette C13; MRP11; multidrug resistance-associated protein 11
    Summary
    Encodes ABCC13/MRP11, a member of the multidrug resistance associated protein MRP/ABCC subfamily. Its expression is induced by gibberellic acid and downregulated by naphthalene acetic acid, abscisic acid, and zeatin.
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    Genomic context

    See ABCC13 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    33
    Sequence:
    Chromosome: 2; NC_003071.7 (3514668..3522658)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene miscRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Minichromosome maintenance (MCM2/3/5) family protein Neighboring gene ncRNA

    General gene information

    NM_001335348.1
    NM_001335349.1
    NM_126770.8

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables ABC-type transporter activity  
    enables ATP hydrolysis activity  
    enables ATPase-coupled transmembrane transporter activity PubMed 
    Component Evidence Code Pubs
    located_in extracellular region  
    located_in plant-type vacuole PubMed 

    General protein information

    Preferred Names
    multidrug resistance-associated protein 11
    NP_178811.7
    • multidrug resistance-associated protein 11 (MRP11); FUNCTIONS IN: ATPase activity, coupled to transmembrane movement of substances; INVOLVED IN: transport, transmembrane transport; LOCATED IN: plasma membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 12 growth stages; CONTAINS InterPro DOMAIN/s: ATPase, AAA+ type, core (InterPro:IPR003593), ABC transporter-like (InterPro:IPR003439), ABC transporter integral membrane type 1 (InterPro:IPR017940), ABC transporter, transmembrane domain, type 1 (InterPro:IPR011527), ABC transporter, transmembrane domain (InterPro:IPR001140), ABC transporter, conserved site (InterPro:IPR017871); BEST Arabidopsis thaliana protein match is: multidrug resistance-associated protein 2 (TAIR:AT2G34660.2); Has 539195 Blast hits to 324792 proteins in 3896 species: Archae - 9326; Bacteria - 437824; Metazoa - 12258; Fungi - 6863; Plants - 5577; Viruses - 6; Other Eukaryotes - 67341 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      3514668..3522658
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001335345.1NP_001323939.1  multidrug resistance-associated protein 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A178U749, A0A1P8AYP5
    2. NM_001335346.1NP_001323940.1  multidrug resistance-associated protein 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AYK9, A0A5S9XQ57, A0A654ESC7
    3. NM_001335347.1NP_001323936.1  multidrug resistance-associated protein 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AYI4, A0A654ESC7
    4. NM_126770.8NP_178811.7  multidrug resistance-associated protein 11 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_178811.7

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4INF8, Q9SKX0
      Conserved Domains (4) summary
      cd03244
      Location:11661385
      ABCC_MRP_domain2; ATP-binding cassette domain 2 of multidrug resistance-associated protein
      cd03250
      Location:558762
      ABCC_MRP_domain1; ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C
      TIGR01271
      Location:1921393
      CFTR_protein; cystic fibrosis transmembrane conductor regulator (CFTR)
      cl00549
      Location:8651121
      ABC_membrane; ABC transporter transmembrane region
    5. NM_001335348.1NP_001323937.1  multidrug resistance-associated protein 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      F4INF8, Q9SKX0
      UniProtKB/TrEMBL
      A0A1P8AYL1
    6. NM_001335349.1NP_001323938.1  multidrug resistance-associated protein 11 [Arabidopsis thaliana]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A1P8AYJ8, A0A5S9XQ57
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